ArticleIntensive care medicine2009
Etiologies and outcome of acute respiratory failure in HIV-infected patients.
Article in Intensive care medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- Longer Prehospitalization and Preintubation Periods in Intubated Non-survivors and ECMO Patients With COVID-19: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2021Pooled it
- Highly active antiretroviral therapy for critically ill HIV patients: A systematic review and meta-analysis.PloS one · 2017Pooled it
- Early antiretroviral therapy for HIV-infected patients admitted to an intensive care unit (EARTH-ICU): A randomized clinical trial.PloS one · 2020Trial
- Evolving Disease Spectrum and Characteristics of People with HIV in Eastern China: A 12-Year Study.Mediterranean journal of hematology and infectious diseases · 2025Article
- Clinical spectrum and prognostic impact of cancer in critically ill patients with HIV: a multicentre cohort study.Annals of intensive care · 2023Article
- High-Flow Nasal Cannula Oxygen Therapy versus Non-Invasive Ventilation in AIDS Patients with Acute Respiratory Failure: A Randomized Controlled Trial.Journal of clinical medicine · 2023Article
- Study on Respiratory Function and Hemodynamics of AIDS Patients with Respiratory Failure.Infection and drug resistance · 2023Article
- Pulmonary Infections and Outcomes in AIDS Patients with Respiratory Failure: A 10-Year Retrospective Review.Infection and drug resistance · 2023Article
- Mortality in patients with acquired human immunodeficiency virus infection hospitalized in an intensive care unit during the period 2017-2019.Scientific reports · 2022Article
- Article
- Performance of a Real Time PCR forJournal of fungi (Basel, Switzerland) · 2022Article
- HIV treatment non-adherence is associated with ICU mortality in HIV-positive critically ill patients.Journal of the Intensive Care Society · 2021Article
- Management of HIV-infected patients in the intensive care unit.Intensive care medicine · 2020Review
- Respiratory virus-associated infections in HIV-infected adults admitted to the intensive care unit for acute respiratory failure: a 6-year bicenter retrospective study (Annals of intensive care · 2020Article
- Indian Antimicrobial Prescription Guidelines in Critically Ill Immunocompromised Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2019Article
- Extracorporeal Membrane Oxygenation in a 29-Year-Old Man withTexas Heart Institute journal · 2018Article
- Successful Treatment of Pulmonary and Cerebral Toxoplasmosis Associated with Pneumocystis Pneumonia in an HIV Patient.Diseases (Basel, Switzerland) · 2017Article
- CLINICAL CHARACTERISTICS, OUTCOMES AND RISK FACTORS FOR DEATH AMONG CRITICALLY ILL PATIENTS WITH HIV-RELATED ACUTE KIDNEY INJURY.Revista do Instituto de Medicina Tropical de Sao Paulo · 2016Article
- Six-month survival of critically ill patients with HIV-related disease and tuberculosis: a retrospective study.BMC infectious diseases · 2016Article
- Characteristics and outcomes of HIV-1-infected patients with acute respiratory distress syndrome.Journal of critical care · 2015Observational
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the etiologies and outcome of acute respiratory failure (ARF) in HIV-infected patients over the first decade of combination antiretroviral therapy (ART) use.
methodsRetrospective study of all HIV-infected patients (n = 147) admitted to a single intensive care unit (ICU) for ARF between 1996 and 2006.
resultsARF revealed the diagnosis of HIV infection in 43 (29.2%) patients. Causes of ARF were bacterial pneumonia (n = 74), Pneumocystis jirovecii pneumonia (PCP, n = 52), other opportunistic infections (n = 19), and noninfectious pulmonary disease (n = 33); the distribution of causes did not change over the 10-year study period. Two or more causes were identified in 33 patients. The 43 patients on ART more frequently had bacterial pneumonia and less frequently had opportunistic infections (P = 0.02). Noninvasive ventilation was needed in 49 patients and endotracheal intubation in 42. Hospital mortality was 19.7%. Factors independently associated with mortality were mechanical ventilation [odds ratio (OR) = 8.48, P < 0.0001], vasopressor use (OR, 4.48; P = 0.03), time from hospital admission to ICU admission (OR, 1.05 per day; P = 0.01), and number of causes (OR, 3.19; P = 0.02). HIV-related variables (CD4 count, viral load, and ART) were not associated with mortality.
conclusionBacterial pneumonia and PCP remain the leading causes of ARF in HIV-infected patients in the ART era. Hospital survival has improved, and depends on the extent of organ dysfunction rather than on HIV-related characteristics.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.