ArticleThe Plant cell2009
Posttranslational elevation of cell wall invertase activity by silencing its inhibitor in tomato delays leaf senescence and increases seed weight and fruit hexose level.
Article in The Plant cell, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 143 papers.
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Who cites it
143 citing papers in PubMed, 313 citations in OpenAlex.
- A sugar flow model predicts cell dynamics, weight, and quality of tomato at varying sink-source ratios and temperatures.Journal of experimental botany · 2026Article
- Genome-Wide Identification of Pineapple AcINH Genes and Functional Characterization ofPlants (Basel, Switzerland) · 2026Article
- Cell Wall Invertase Inhibitor SlINVINH1 Acts as a Negative Regulator in Fruit Ripening of Tomato.Plants (Basel, Switzerland) · 2026Article
- ConstitutiveInternational journal of molecular sciences · 2025Article
- A Review of Differential Plant Responses to Drought, Heat, and Combined Drought + Heat Stress.Current issues in molecular biology · 2025Review
- Genome-Wide Characterization of Kiwifruit Invertase Gene Family Reveals Roles ofInternational journal of molecular sciences · 2025Article
- Sucrose transport gene FaSWEET9a regulated by FaDOF2 transcription factor promotes sucrose accumulation in strawberry.Plant cell reports · 2025Article
- Tonoplast sugar transporters coordinately regulate tomato fruit development and quality.Plant communications · 2025Article
- Raffinose family oligosaccharide hydrolysis by alkaline α-galactosidase CsAGA2 controls seed development in cucumber.The Plant cell · 2025Article
- Cell Wall Invertase 4 Governs Sucrose-Hexose Homeostasis in the Apoplast to Regulate Wood Development in Poplar.Plants (Basel, Switzerland) · 2025Article
- Identification of the SWEET gene family and functional characterization of PsSWEET1a and PsSWEET17b in the regulation of sugar accumulation in 'Fengtang' plum (Prunus salicina Lindl.).BMC plant biology · 2025Article
- Siblicide between fertilized and unfertilized ovaries within the maize ear.Communications biology · 2025Article
- Genome-Wide Identification and Expression Profiling of the Invertase Genes Involved in Sugar Metabolism and Accumulation inInternational journal of molecular sciences · 2025Article
- Enzyme Repertoires and Genomic Insights into Lycium barbarum Pectin Polysaccharide Biosynthesis.Genomics, proteomics & bioinformatics · 2025Article
- A vacuolar invertase geneHorticulture research · 2025Article
- Diversity of Gibberellin 2-oxidase genes in the barley genome offers opportunities for genetic improvement.Journal of advanced research · 2024Article
- Cell Wall Invertases from Maternal Tissues Modulate Sucrose Flux in Apoplastic Pathways During Rice Anther and Seed Development.International journal of molecular sciences · 2024Article
- Genome-wide analysis of the passion fruit invertase gene family reveals involvement of PeCWINV5 in hexose accumulation.BMC plant biology · 2024Article
- Sugar import mediated by sugar transporters and cell wall invertases for seed development inHorticulture research · 2024Article
- Phytochemical Profiling and Bioactive Potential of Grape Seed Extract in Enhancing Salinity Tolerance ofPlants (Basel, Switzerland) · 2024Article
83 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Invertase plays multiple pivotal roles in plant development. Thus, its activity must be tightly regulated in vivo. Emerging evidence suggests that a group of small proteins that inhibit invertase activity in vitro appears to exist in a wide variety of plants. However, little is known regarding their roles in planta. Here, we examined the function of INVINH1, a putative invertase inhibitor, in tomato (Solanum lycopersicum). Expression of a INVINH1:green fluorescent protein fusion revealed its apoplasmic localization. Ectopic overexpression of INVINH1 in Arabidopsis thaliana specifically reduced cell wall invertase activity. By contrast, silencing its expression in tomato significantly increased the activity of cell wall invertase without altering activities of cytoplasmic and vacuolar invertases. Elevation of cell wall invertase activity in RNA interference transgenic tomato led to (1) a prolonged leaf life span involving in a blockage of abscisic acid-induced senescence and (2) an increase in seed weight and fruit hexose level, which is likely achieved through enhanced sucrose hydrolysis in the apoplasm of the fruit vasculature. This assertion is based on (1) coexpression of INVINH1 and a fruit-specific cell wall invertase Lin5 in phloem parenchyma cells of young fruit, including the placenta regions connecting developing seeds; (2) a physical interaction between INVINH1 and Lin5 in vivo; and (3) a symplasmic discontinuity at the interface between placenta and seeds. Together, the results demonstrate that INVINH1 encodes a protein that specifically inhibits the activity of cell wall invertase and regulates leaf senescence and seed and fruit development in tomato by limiting the invertase activity in planta.
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