Evidence map›Paper›PMID 19574017›Full record

Trial reportJournal of substance abuse treatment2010

A randomized trial of transcutaneous electric acupoint stimulation as adjunctive treatment for opioid detoxification.

Christina S Meade, Scott E Lukas, Leah J McDonald, Garrett M Fitzmaurice, Jessica A Eldridge, Nancy Merrill, Roger D Weiss

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of substance abuse treatment, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00742170 (Transdermal Electroacupuncture for Opioid Detoxification), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
6.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00742170 phase1 / phase2completednot on this map

Transdermal Electroacupuncture for Opioid Detoxification

TypeinterventionalSponsorMclean HospitalRan2007 to 2010Enrolled48ConditionsOpioid DependencyArmsElectroacupuncture
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Buprenorphine for managing opioid withdrawal.The Cochrane database of systematic reviews · 2017
    Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Targeting Neuronal Networks with Combined Drug and Stimulation Paradigms Guided by Neuroimaging to Treat Brain Disorders.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2015
    Review
  15. Trial of tramadol plus gabapentin for opioid detoxification.Iranian Red Crescent medical journal · 2015
    Article
  16. Review
  17. Article
  18. Article
  19. Newer approaches to opioid detoxification.Industrial psychiatry journal · 2012
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Christina S MeadeHarvard Medical School, Department of Psychiatry, Boston, MA 02115, USA. christina.meade@duke.edu
Scott E Lukas
Leah J McDonald
Garrett M Fitzmaurice
Jessica A Eldridge
Nancy Merrill
Roger D Weiss
McLean Hospital · USHarvard University · US

Funding

Project 4 - Chinese Herbal Medicine to Treat Alcohol &Drug AbuseP01AT002038 · NCCIH · MC LEAN HOSPITAL (BELMONT, MA) · PI LUKAS, SCOTT E · 2004 to 2008
$5.8M
Training In Drug Abuse and Brain ImagingT32DA015036 · NIDA · MC LEAN HOSPITAL (BELMONT, MA) · PI SCOTT E LUKAS · 2002 to 2026
$5.3M
Mentoring in Drug Abuse and Dual Diagnosis ResearchK24DA022288 · NIDA · MCLEAN HOSPITAL · PI WEISS, ROGER D. · 2007 to 2016
$1.8M
PHARMACOLOGICAL AND BEHAVIORAL INDICES OF DRUG ABUSEK05DA000343 · NIDA · MC LEAN HOSPITAL (BELMONT, MA) · PI LUKAS, SCOTT E · 1997 to 2008
$1.1M
NCCIH NIH HHS P01 AT002038NCCIH NIH HHS P01AT002038NIDA NIH HHS K05 DA000343NIDA NIH HHS K05DA000343NIDA NIH HHS K24 DA022288NIDA NIH HHS K24DA022288NIDA NIH HHS T32 DA015036NIDA NIH HHS T32DA01536
6 · The paper itself

Abstract

This pilot study tested the effectiveness of transcutaneous electric acupoint stimulation (TEAS) as an adjunctive treatment for inpatients receiving opioid detoxification with buprenorphine-naloxone at a private psychiatric hospital. Participants (N = 48) were randomly assigned to active or sham TEAS and received three 30-minute treatments daily for 3 to 4 days. In active TEAS, current was set to maximal tolerable intensity (8-15 mA); in sham TEAS, it was set to 1 mA. By 2 weeks postdischarge, participants in active TEAS were less likely to have used any drugs (35% vs. 77%, p < .05). They also reported greater improvements in pain interference (F = 4.52, p < .05) and physical health (F = 4.84, p < .01) over time. TEAS is an acceptable, inexpensive adjunctive treatment that is feasible to implement on an inpatient unit and may be a beneficial adjunct to pharmacological treatments for opioid detoxification.

Indexed as

Acupuncture PointsAdolescentAdultAnalgesics, OpioidAnalysis of VarianceBuprenorphineChi-Square DistributionCombined Modality TherapyDrug Administration ScheduleFemaleHealth StatusHumansMaleMiddle AgedNaloxoneNarcotic AntagonistsAnalgesics, OpioidBuprenorphineNaloxoneNarcotic Antagonists

Identifiers

PMID19574017
PMCPMC2789908
OpenAlexW1964270301

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.