ReviewAlimentary pharmacology & therapeutics2009
Review article: gastric electrical stimulation for gastroparesis--physiological foundations, technical aspects and clinical implications.
Review in Alimentary pharmacology & therapeutics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Guideline
- Open-label pilot study: Non-invasive vagal nerve stimulation improves symptoms and gastric emptying in patients with idiopathic gastroparesis.Neurogastroenterology and motility · 2020Trial
- Mini-laparotomy with Adjunctive Care versus Laparoscopy for Placement of Gastric Electrical Stimulation.The American surgeon · 2016Trial
- Gastric electrical stimulation with Enterra therapy improves symptoms of idiopathic gastroparesis.Neurogastroenterology and motility · 2013Trial
- Non-invasive Vagal Nerve Stimulation Decreases the Need for Rescue Medication for Nausea Exacerbation in Patients with Chronic Nausea and Vomiting.Digestive diseases and sciences · 2026Article
- Neuromodulation for functional upper gastrointestinal diseases.Gut microbiota and integrative wellness · 2023Article
- Nausea and Vomiting in 2021: A Comprehensive Update.Journal of clinical gastroenterology · 2021Review
- Ingestible transiently anchoring electronics for microstimulation and conductive signaling.Science advances · 2020Article
- Gastroparesis in the 2020s: New Treatments, New Paradigms.Current gastroenterology reports · 2020Review
- Effectiveness of gastric electrical stimulation in gastroparesis: Results from a large prospectively collected database of national gastroparesis registries.Neurogastroenterology and motility · 2019Article
- Diabetic Gastroparesis.Endocrine reviews · 2019Review
- Gastric Electric Stimulation for Refractory Gastroparesis.Journal of clinical outcomes management : JCOM · 2019Article
- A Miniature Configurable Wireless System for Recording Gastric Electrophysiological Activity and Delivering High-Energy Electrical Stimulation.IEEE journal on emerging and selected topics in circuits and systems · 2018Article
- A Wireless Implant for Gastrointestinal Motility Disorders.Micromachines · 2018Article
- Acute Slow Wave Responses to High-Frequency Gastric Electrical Stimulation in Patients With Gastroparesis Defined by High-Resolution Mapping.Neuromodulation : journal of the International Neuromodulation Society · 2016Article
- Neurostimulation of the gastrointestinal tract: review of recent developments.Neuromodulation : journal of the International Neuromodulation Society · 2015Review
- Gastric stasis in migraineurs: etiology, characteristics, and clinical and therapeutic implications.Cephalalgia : an international journal of headache · 2013Review
- Gastric stimulation for weight loss.World journal of gastroenterology · 2012Review
- Gastric electrical stimulation for gastroparesis: a goal greatly pursued, but not yet attained.World journal of gastroenterology · 2011Article
- Gastroparesis and functional dyspepsia: excerpts from the AGA/ANMS meeting.Neurogastroenterology and motility · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundApplication of electrical stimulation to the gut, primarily the stomach, has rapidly advanced in the last two decades, from mostly animal studies to the clinical arena. Most studies focused on the use of electrical stimulation for gastroparesis, the only approved indication for such intervention.
aimTo review the physiological basis of gastric electrical activity and the technical aspects and clinical outcome of gastric electrical stimulation (GES) for gastroparesis.
methodsPubMed search from 1966 to 2009, using gastroparesis and GES as search terms. Areas in focus were systematically reviewed.
resultsThe literature consists of open-label studies, mostly from single centres, published in the last decade. Improvement in symptoms, quality of life and nutritional status was reported by most studies. Physiologically, stimulation parameters approved in clinical practice do not regulate gastric slow wave activity and have inconsistent effect on gastric emptying. The mechanism of action of GES is not fully known, but data support modulation of gastric biomechanical activity and afferent neural mechanisms.
conclusionsGastric electrical stimulation is a helpful intervention in recalcitrant gastroparesis. Controlled studies and better understanding of mechanisms of action of electrical stimulation are needed to evaluate further the clinical utility of this intervention and to exploit its therapeutic potential better.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.