ArticleBritish journal of haematology2009
Common genetic variants in candidate genes and risk of familial lymphoid malignancies.
Article in British journal of haematology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Association of Interleukin-10 -3575T>A and -1082A>G polymorphisms with non-Hodgkin lymphoma susceptibility: a comprehensive review and meta-analysis.Molecular genetics and genomics : MGG · 2015Pooled it
- IL-6 -174G>C polymorphism and cancer risk: a meta-analysis involving 29,377 cases and 37,739 controls.Molecular biology reports · 2011Pooled it
- The landscape of rare genetic variants in familial Waldenström macroglobulinemia.Blood neoplasia · 2024Article
- Current approach to Waldenström macroglobulinemia.Blood reviews · 2023Review
- The epidemiology of Waldenström macroglobulinemia.Seminars in hematology · 2023Review
- Tumor necrosis factor-related apoptosis inducing ligand gene polymorphisms are correlated with gastric cancer in central China.Pharmaceutical research · 2015Article
- Little association between the interleukin 10-3575T/A polymorphism and cancer risk: pooled analysis of 15608 cancer cases and 17539 controls.International journal of clinical and experimental medicine · 2015Article
- Association between TRAIL gene polymorphisms and the susceptibility and severity of lumbar disc degeneration.International journal of clinical and experimental pathology · 2015Article
- Medical history, lifestyle, family history, and occupational risk factors for lymphoplasmacytic lymphoma/Waldenström's macroglobulinemia: the InterLymph Non-Hodgkin Lymphoma Subtypes Project.Journal of the National Cancer Institute. Monographs · 2014Article
- Rare missense variants in POT1 predispose to familial cutaneous malignant melanoma.Nature genetics · 2014Article
- Epidemiological Overview of Hodgkin Lymphoma across the Mediterranean Basin.Mediterranean journal of hematology and infectious diseases · 2014Review
- Inherited polymorphisms in hyaluronan synthase 1 predict risk of systemic B-cell malignancies but not of breast cancer.PloS one · 2014Article
- Association of the four common polymorphisms in interleukin-10 (rs1800890, rs1800896, rs1800871, and rs1800872) with non-Hodgkin's lymphoma risk: a meta-analysis.International journal of clinical and experimental medicine · 2014Article
- Waldenström macroglobulinemia: clinical and immunological aspects, natural history, cell of origin, and emerging mouse models.ISRN hematology · 2013Review
- Candidate genes of Waldenström's macroglobulinemia: current evidence and research.The application of clinical genetics · 2013Article
- Article
- Influence of polymorphisms in innate immunity genes on susceptibility to invasive aspergillosis after stem cell transplantation.PloS one · 2011Article
- IL-2-inducible T-cell kinase deficiency: clinical presentation and therapeutic approach.Haematologica · 2011Article
- TNF superfamily gene polymorphism as prognostic factor in early breast cancer.Journal of cancer research and clinical oncology · 2010Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
Familial aggregation, linkage and case-control studies support the role of germline genes in the aetiology of lymphoid malignancies. To further examine the role of genetic variation underlying susceptibility, we analysed 1536 single nucleotide polymorphisms in 152 genes involved in apoptosis, DNA repair, immune response and oxidative stress pathways among a unique sample of 165 unrelated familial cases including patients with chronic lymphocytic leukaemia (CLL), Waldenström macroglobulinaemia (WM) and Hodgkin lymphoma (HL), and 107 spouse controls. We confirmed previous studies showing a polymorphism in the IL10 promoter (rs1800890/-3575T>A) to be associated with non-Hodgkin lymphoma, as this allele was found to be associated with both CLL and WM. We also confirmed the role of IL6 variation to be associated with HL. Polymorphisms in TNFSF10 were associated with both CLL and WM. Future replication and functional studies are needed to clarify the role of these genetic variants. Finally, our data further support the close association of WM and CLL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.