Evidence map›Paper›PMID 19572093›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2010

Women with hip fracture experience greater loss of geometric strength in the contralateral hip during the year following fracture than age-matched controls.

L Reider, T J Beck, M C Hochberg, W G Hawkes, D Orwig, J A YuYahiro, J R Hebel, J Magaziner, Study of Osteoporotic Fractures Research Group

Abstract readMulticenter Study
In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Effects of Multicomponent Home-Based Intervention on Muscle Composition, Fitness, and Bone Density After Hip Fracture.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Trial
  2. Trial
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Older men who sustain a hip fracture experience greater declines in bone mineral density at the contralateral hip than non-fractured comparators.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Article
  9. Automated DXA-based finite element analysis for hip fracture risk stratification: a cross-sectional study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Article
  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

L ReiderJohns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA. lsemanic@jhsph.edu
T J Beck
M C Hochberg
W G Hawkes
D Orwig
J A YuYahiro
J R Hebel
J Magaziner
Study of Osteoporotic Fractures Research Group

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
Study of Osteoporotic FracturesR01AG005407 · NIA · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI CUMMINGS, STEVEN RON, YAFFE, KRISTINE · 1986 to 2016
$23.2M
Sequelae of Hip Fracture in Men: An Epidemiologic StudyR37AG009901 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY · 1992 to 2018
$11.3M
Changes in Sleep and Cognition in Older WomenR01AG026720 · NIA · CALIFORNIA PACIFIC MED CTR RES INSTITUTE · PI STONE, KATIE L, YAFFE, KRISTINE · 2006 to 2016
$7.5M
Study of Osteoporotic FracturesR01AG005394 · NIA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI ENSRUD, KRISTINE · 1986 to 2015
$6.1M
STUDY OF OSTEOPOROTIC FRACTURES: VERTEBRAL FRACTURESR01AR035583 · NIAMS · KAISER FOUNDATION RESEARCH INSTITUTE · PI HILLIER, TERESA A · 1986 to 2005
$3.2M
Study of Osteoporotic Fractures (SOF)R01AG027574 · NIA · KAISER FOUNDATION RESEARCH INSTITUTE · PI HILLIER, TERESA A · 2006 to 2015
$2.6M
Study of Osteoporotic Fractures (SOF)-Pittsburgh ClinicR01AG027576 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CAULEY, JANE ANN · 2006 to 2015
$2.4M
Study of Osteoporotic FracturesR01AR035582 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CAULEY, JANE · 1986 to 2005
$2.4M
Determinants of Recovery Following Hip FractureR01AG018668 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY STEVEN · 2001 to 2004
$2.3M
Study of Osteoporotic FracturesR01AR035584 · NIAMS · UNIVERSITY OF MARYLAND BALTIMORE · PI HOCHBERG, MARC C. · 1986 to 2005
$2.1M
NIAMS NIH HHS AR35582NIAMS NIH HHS AR35583NIAMS NIH HHS AR35584NIAMS NIH HHS R01 AR035582NIAMS NIH HHS R01 AR035583NIAMS NIH HHS R01 AR035584NIA NIH HHS 2 R01 AG005394-22A1NIA NIH HHS 2 R01 AG027574-22A1NIA NIH HHS AG026720NIA NIH HHS AG05394NIA NIH HHS AG05407NIA NIH HHS P30 AG028747NIA NIH HHS R01 AG005394NIA NIH HHS R01 AG005407NIA NIH HHS R01 AG018668NIA NIH HHS R01 AG026720NIA NIH HHS R01 AG027574NIA NIH HHS R01 AG027576NIA NIH HHS R01 AG027576-22NIA NIH HHS R37 AG009901
6 · The paper itself

Abstract

unlabelledThis study examined femur geometry underlying previously observed decline in BMD of the contralateral hip in older women the year following hip fracture compared to non-fractured controls. Compared to controls, these women experienced a greater decline in indices of bone structural strength, potentially increasing the risk of a second fracture.

introductionThis study examined the femur geometry underlying previously observed decline in BMD of the contralateral hip in the year following hip fracture compared to non-fractured controls.

methodsGeometry was derived from dual-energy X-ray absorptiometry scan images using hip structural analysis from women in the third cohort of the Baltimore Hip Studies and from women in the Study of Osteoporotic Fractures. Change in BMD, section modulus (SM), cross-sectional area (CSA), outer diameter, and buckling ratio (BR) at the narrow neck (NN), intertrochanteric (IT), and shaft (S) regions of the hip were compared.

resultsWider bones and reduced CSA underlie the significantly lower BMD observed in women who fractured their hip resulting in more fragile bones expressed by a lower SM and higher BR. Compared to controls, these women experienced a significantly greater decline in CSA (-2.3% vs. -0.2%NN, -3.2% vs. -0.5%IT), SM (-2.1% vs. -0.2%NN, -3.9% vs. -0.6%IT), and BMD (-3.0% vs. -0.8%NN, -3.3% vs. -0.6%IT, -2.3% vs. -0.2%S) and a greater increase in BR (5.0% vs. 2.1%NN, 6.0% vs. 1.3%IT, 4.4% vs. 1.0%S) and shaft outer diameter (0.9% vs. 0.1%).

conclusionThe contralateral femur continued to weaken during the year following fracture, potentially increasing the risk of a second fracture.

Indexed as

Absorptiometry, PhotonAgedAged, 80 and overBone DensityEpidemiologic MethodsFemaleFemurFemur NeckHip FracturesHumansOsteoporotic Fractures

Identifiers

PMID19572093
PMCPMC2847041

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.