ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2009
Early origin of the bilaterian developmental toolkit.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27 citing papers in PubMed, 139 citations in OpenAlex.
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- Widespread retention of ohnologs in key developmental gene families following whole-genome duplication in arachnopulmonates.G3 (Bethesda, Md.) · 2021Article
- A largely invariant marine dissolved organic carbon reservoir across Earth's history.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
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- Development and evolution of the metazoan heart.Developmental dynamics : an official publication of the American Association of Anatomists · 2019Review
- Stem cell differentiation trajectories inScience (New York, N.Y.) · 2019Article
- Highly regulated growth and development of the Ediacara macrofossil Dickinsonia costata.PloS one · 2017Article
- Ancient role ofHereditas · 2017Article
- Synthetic transitions: towards a new synthesis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
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- Deep developmental transcriptome sequencing uncovers numerous new genes and enhances gene annotation in the sponge Amphimedon queenslandica.BMC genomics · 2015Article
- Emergence of multicellularity in a model of cell growth, death and aggregation under size-dependent selection.Journal of the Royal Society, Interface · 2015Article
- The TALE face of Hox proteins in animal evolution.Frontiers in genetics · 2015Article
- Correcting for differential transcript coverage reveals a strong relationship between alternative splicing and organism complexity.Molecular biology and evolution · 2014Article
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1 author at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Whole-genome sequences from the choanoflagellate Monosiga brevicollis, the placozoan Trichoplax adhaerens and the cnidarian Nematostella vectensis have confirmed results from comparative evolutionary developmental studies that much of the developmental toolkit once thought to be characteristic of bilaterians appeared much earlier in the evolution of animals. The diversity of transcription factors and signalling pathway genes in animals with a limited number of cell types and a restricted developmental repertoire is puzzling, particularly in light of claims that such highly conserved elements among bilaterians provide evidence of a morphologically complex protostome-deuterostome ancestor. Here, I explore the early origination of elements of what became the bilaterian toolkit, and suggest that placozoans and cnidarians represent a depauperate residue of a once more diverse assemblage of early animals, some of which may be represented in the Ediacaran fauna (c. 585-542 Myr ago).
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