ArticleJournal of virology2009
Characterization of a novel flavivirus from mosquitoes in northern europe that is related to mosquito-borne flaviviruses of the tropics.
Article in Journal of virology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 1 synthesis or guideline pooled it, 106 citations in OpenAlex.
- Pooled it
- Transcriptomic and RNAi-mediated antiviral response to Kamiti River virus infection in Aedes albopictus U4.4 cells.Scientific reports · 2026Article
- NS4B and NS5 mutations expand the temperature range permissive for the replication of dual-host affiliated insect-specific flaviviruses in mosquito cells.Archives of virology · 2026Article
- Review
- Insect-specific viruses: transmission dynamics and biological control strategies against arboviruses.Frontiers in microbiology · 2025Review
- Orthoflavivirus Lammi in Russia: Possible Transovarial Transmission and Trans-Stadial Survival inViruses · 2024Article
- Longitudinal Study of Viral Diversity Associated with Mosquito Species Circulating in Cambodia.Viruses · 2023Article
- The Importance of Epigallocatechin as a Scaffold for Drug Development against Flaviviruses.Pharmaceutics · 2023Article
- Modification of the Folmer primers for the cytochrome c oxidase gene facilitates identification of mosquitoes.Parasites & vectors · 2022Article
- Characterisation of the RNA Virome of NineViruses · 2022Article
- Replication is the key barrier during the dual-host adaptation of mosquito-borne flaviviruses.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Development of Real-Time Molecular Assays for the Detection of Wesselsbron Virus in Africa.Microorganisms · 2022Article
- Transcriptome Analysis of anInternational journal of molecular sciences · 2022Article
- Widespread interspecific phylogenetic tree incongruence between mosquito-borne and insect-specific flaviviruses at hotspots originally identified in Zika virus.Virus evolution · 2022Article
- Small RNA Response to Infection of the Insect-Specific Lammi Virus and Hanko Virus in anViruses · 2021Article
- Review
- Isolation of a novel insect-specific flavivirus with immunomodulatory effects in vertebrate systems.Virology · 2021Article
- Development of genus-specific universal primers for the detection of flaviviruses.Virology journal · 2021Article
- Mechanisms Underlying Host Range Variation in Flavivirus: From Empirical Knowledge to Predictive Models.Journal of molecular evolution · 2021Review
- Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A novel flavivirus was isolated from mosquitoes in Finland, representing the first mosquito-borne flavivirus from Northern Europe. The isolate, designated Lammi virus (LAMV), was antigenically cross-reactive with other flaviviruses and exhibited typical flavivirus morphology as determined by electron microscopy. The genomic sequence of LAMV was highly divergent from the recognized flaviviruses, and yet the polyprotein properties resembled those of mosquito-borne flaviviruses. Phylogenetic analysis of the complete coding sequence showed that LAMV represented a distinct lineage related to the Aedes sp.-transmitted human pathogenic flaviviruses, similarly to the newly described Nounané virus (NOUV), a flavivirus from Africa (S. Junglen et al., J. Virol. 83:4462-4468, 2009). Despite the low sequence homology, LAMV and NOUV were phylogenetically grouped closely, likely representing separate species of a novel group of flaviviruses. Despite the biological properties preferring replication in mosquito cells, the genetic relatedness of LAMV to viruses associated with vertebrate hosts warrants a search for disease associations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.