Evidence map›Paper›PMID 19570621›Full record

Trial reportDrug and alcohol dependence2009

Delayed reward discounting predicts treatment response for heavy drinkers receiving smoking cessation treatment.

James MacKillop, Christopher W Kahler

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Drug and alcohol dependence, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 145 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
145citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

145 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Incentives for smoking cessation.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Pooled it
  3. Incentives for smoking cessation.The Cochrane database of systematic reviews · 2019
    Pooled it
  4. Pooled it
  5. Pooled it
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  7. Pooled it
  8. Pooled it
  9. Trial
  10. Working Memory Training Reduces Cigarette Smoking Among Low-Income Individuals With Elevated Delay Discounting.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022
    Trial
  11. Internal Validity of Two Promising Methods of Altering Temporal Orientation among Cigarette Smokers.International journal of environmental research and public health · 2021
    Trial
  12. Trial
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  17. Delay discounting in adults receiving treatment for marijuana dependence.Experimental and clinical psychopharmacology · 2013
    Trial
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  20. N-acetylcysteine normalizes glutamate levels in cocaine-dependent patients: a randomized crossover magnetic resonance spectroscopy study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012
    Trial

85 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

James MacKillopDepartment of Psychology, University of Georgia, Athens, GA 30677, USA. jmackill@uga.edu
Christopher W Kahler

Funding

Improving Smoking Cessation Outcomes in Heavy DrinkersR01DA015534 · NIDA · BROWN UNIVERSITY · PI KAHLER, CHRISTOPHER W. · 2003 to 2006
$1.6M
Enhancing Alcoholism Pharmacotherapy Research via Behavioral EconomicsK23AA016936 · NIAAA · UNIVERSITY OF GEORGIA · PI MACKILLOP, JAMES · 2008 to 2012
$805k
NIAAA NIH HHS K23 AA016936NIDA NIH HHS R01 DA015534NIDA NIH HHS R01 DA15534
6 · The paper itself

Abstract

Delayed reward discounting (DRD) is a behavioral economic index of impulsivity that reflects the extent to which an individual devalues a reward based on its delay in time (i.e., preference for smaller immediate rewards relative to larger delayed rewards). Current smokers exhibit greater DRD compared to non-smokers, but also exhibit greater DRD compared to ex-smokers, suggesting that either DRD is inversely associated with successful smoking cessation or that smoking cessation itself reduces DRD. In a sample of treatment-seeking smokers (n=57, 61% male, 85% Caucasian) participating in a randomized controlled smoking cessation trial, the current study prospectively examined DRD for money in general and at three magnitudes in relation to time to the participants' first lapse to smoking. Survival analysis using Cox proportional-hazards regression revealed that DRD predicted days to first lapse (ps<.05-.01) and did so beyond nicotine dependence, sensation-seeking, and income in covariate analyses, with the exception of small magnitude discounting. In addition, dichotomous comparisons revealed significantly more impulsive baseline discounting for individuals who had lapsed by the two-week and eight-week follow-up visits. These findings indicate that high levels of DRD reflect a risk factor for poor smoking cessation treatment response. Interrelationships among the variables assessed and clinical strategies to improve outcomes for smokers who are high in DRD are discussed.

Indexed as

RewardAdultAlcohol DrinkingCounselingFemaleHumansMaleModels, PsychologicalNicotineRisk-TakingSmokingSmoking CessationTobacco Use DisorderTreatment OutcomeNicotine

Identifiers

PMID19570621
PMCPMC2740648

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.