Evidence map›Paper›PMID 19570493›Full record

ReviewCurrent urology reports2009

Phenotypic approach to the management of chronic prostatitis/chronic pelvic pain syndrome.

J Curtis Nickel, Daniel Shoskes

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Current urology reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07685847 (Clinical Evaluation of the Efficacy and Safety of a Medical Device in the Form of Rectal Suppositories), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07685847 narecruitingnot on this mapstarted 2025, after this paper: background citation

Clinical Evaluation of the Efficacy and Safety of a Medical Device in the Form of Rectal Suppositories (Prospidol®) for the Treatment of Symptoms Associated With Chronic Prostatitis/Chronic Pelvic Pain Syndrome.

TypeinterventionalSponsorS&R Farmaceutici S.p.A.Ran2025 to 2026Enrolled40ConditionsChronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)ArmsProspidol suppository
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. [Chronic prostatitis/chronic pelvic pain syndrome].Urologie (Heidelberg, Germany) · 2023
    Review
  4. Article
  5. Article
  6. The evolving clinical picture of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS): A look at 1310 patients over 16 years.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2018
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

J Curtis NickelDepartment of Urology, Queen's University, Kingston General Hospital, Kingston, Ontario, Canada. jcn@queensu.ca
Daniel Shoskes
Kingston General Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is no one unifying etiological mechanism or specific curative therapy for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). However, there is sufficient evidence to suggest that each of the proposed mechanisms may be important in some patients, and that many of our evaluated treatments do in fact work in subgroups of patients. We hypothesize that CP/CPPS patients are not a homogenous group suffering from a single disease entity. Rather, CP/CPPS patients are actually unique individuals with differing clinical phenotypes based on various etiological mechanisms with distinctive symptom complexes and progression trajectories. We call this the "Snow Flake Hypothesis." We propose the UPOINT (urinary, psychosocial, organ-specific, infection, neurologic/systemic, and tenderness domains) clinical phenotyping classification; we have validated the concept in a CP/CPPS cohort and have suggested that phenotypically directed therapy will improve our clinical treatment outcomes.

Indexed as

HumansMalePhenotypeProstatitis

Identifiers

PMID19570493
OpenAlexW2057636756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.