ArticleTobacco induced diseases2002
Cigarette smoking: an important renal risk factor - far beyond carcinogenesis.
Article in Tobacco induced diseases, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Association of smoking and cardiometabolic parameters with albuminuria in people with type 2 diabetes mellitus: a systematic review and meta-analysis.Acta diabetologica · 2019Pooled it
- Racial Disparities and Preventive Measures to Renal Cell Carcinoma.International journal of environmental research and public health · 2018Pooled it
- Kidney Dysfunction, Biochemical Changes, DNA Alteration, and MAPKs Regulation Following Chronic Exposure to Regular and Occasional Hookah Smoke in Mice.Oxidative medicine and cellular longevity · 2026Article
- Assessment of the Effects of Cigarette Smoke on the Renal Morphology of WISTAR Rats.Journal of applied toxicology : JAT · 2026Article
- Association between fibroblast growth factor 19 and depressive symptoms: the moderating role of smoking.Acta neuropsychiatrica · 2025Article
- Renal Hyperfiltration as a New Mechanism of Smoking-Related Mortality.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Article
- Epidemiology of tobacco use in dialysis patients in France and survey of nephrologists' involvement in counseling on tobacco discontinuation.Journal of nephrology · 2024Article
- Active smoking in urban households: An association between urinary cotinine metabolite level and serum eGFR concentration.Tobacco induced diseases · 2024Article
- Impact of passive smoking on renal vascular morphology.Einstein (Sao Paulo, Brazil) · 2022Article
- Smoking accelerates renal cystic disease and worsens cardiac phenotype in Pkd1-deficient mice.Scientific reports · 2021Article
- Sleeping, Smoking, and Kidney Diseases: Evidence From the NHANES 2017-2018.Frontiers in medicine · 2021Article
- Mendelian randomization case-control PheWAS in UK Biobank shows evidence of causality for smoking intensity in 28 distinct clinical conditions.EClinicalMedicine · 2020Article
- Cigarette smoke inhalation aggravates diabetic kidney injury in rats.Toxicology research · 2019Article
- Helping Patients With ESRD and Earlier Stages of CKD to Quit Smoking.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2018Review
- LncRNA-SARCC suppresses renal cell carcinoma (RCC) progression via altering the androgen receptor(AR)/miRNA-143-3p signals.Cell death and differentiation · 2017Article
- Sub-acute administration of lower doses of nicotine caused sex-dependent improvement of renal function in Wistar rats.Toxicology reports · 2017Article
- Smoking has no impact on survival and it is not associated with ACE gene I/D polymorphism in hemodialysis patients.Journal of the renin-angiotensin-aldosterone system : JRAAS · 2017Article
- Cigarette smoking and cardio-renal events in patients with atherosclerotic renal artery stenosis.PloS one · 2017Article
- Cigarette smoking causes epigenetic changes associated with cardiorenal fibrosis.Physiological genomics · 2016Article
- Impact of smoking status on survival after cytoreductive nephrectomy for metastatic renal cell carcinoma.World journal of urology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, it has become apparent that smoking has a negative impact on renal function, being one of the most important remediable renal risk factors. It has been clearly shown that the risk for high-normal urinary albumin excretion and microalbuminuria is increased in smoking compared to non-smoking subjects of the general population. Data from the Multiple Risk Factor Intervention Trial (MRFIT) indicate that at least in males, smoking increases the risk to reach end-stage renal failure. Smoking is particularly "nephrotoxic" in older subjects, subjects with essential hypertension and patients with preexisting renal disease. Of interest, the magnitude of the adverse renal effect of smoking seems to be independent of the underlying renal disease. Death-censored renal graft survival is decreased in smokers, indicating that smoking also damages the renal transplant. Cessation of smoking has been show to reduce the rate of progression of renal failure both in patients with renal disease or a renal transplant. The mechanisms of smoking-induced renal damage are only partly understood and comprise acute hemodynamic (e.g., increase in blood pressure and presumably intraglomerular pressure) and chronic effects (e.g., endothelial cell dysfunction). Renal failure per se leads to an increased cardiovascular risk. The latter is further aggravated by smoking. Particularly survival of smokers with diabetes mellitus on hemodialysis is abysmal. In the present review article the current state of knowledge about the renal risks of smoking is reviewed. It is the aim of the article to point out that smoking not only increases the risk of renal cell carcinoma or uroepithelial cell carcinoma, but also the risk of a faster decline of renal function. The latter is a relatively new negative aspect which has not been widely recognized.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.