Evidence map›Paper›PMID 19568349›Full record

ArticleOrganogenesis2009

Development of kidney glomerular endothelial cells and their role in basement membrane assembly.

Dale R Abrahamson

Open access · bronzeAbstract read
In one paragraph

Article in Organogenesis, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 61 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Collagen IV of basement membranes: II. Emergence of collagen IVThe Journal of biological chemistry · 2023
    Article
  7. Review
  8. Review
  9. Building Complex Life Through Self-Organization.Tissue engineering. Part A · 2019
    Review
  10. Development of the renal vasculature.Seminars in cell & developmental biology · 2019
    Review
  11. Article
  12. Review
  13. Forensic Aspects of Perinatal Deaths.Academic forensic pathology · 2018
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Dale R AbrahamsonDepartment of Anatomy and Cell Biology; University of Kansas Medical Center; Kansas City, Kansas USA.
Kansas City Public Schools · US

Funding

TYPE IV COLLAGEN, LAMININS, AND INTEGRINS IN NORMAL AND DISEASED GLOMERULIP01DK065123 · NIDDK · VANDERBILT UNIVERSITY · PI HUDSON, BILLY GERALD · 2003 to 2012
$12.9M
RECEPTOR/LIGAND SIGNALS FOR KIDNEY VASCULAR DEVELOPMENTR01DK052483 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI ABRAHAMSON, DALE R · 1997 to 2008
$2.0M
NIDDK NIH HHS P01 DK065123NIDDK NIH HHS R01 DK052483
6 · The paper itself

Abstract

Data showing that the embryonic day 12 (E12) mouse kidney contains its own pool of endothelial progenitor cells is presented. Mechanisms that regulate metanephric endothelial recruitment and differentiation, including the hypoxia-inducible transcription factors and vascular endothelial growth factor/vascular endothelial growth factor receptor signaling system, are also discussed. Finally, evidence that glomerular endothelial cells contribute importantly to assembly of the glomerular basement membrane (GBM), especially the laminin component, is reviewed. Together, this forum offers insights on blood vessel development in general, and formation of the glomerular capillary in particular, which inarguably is among the most unique vascular structures in the body.

Indexed as

glomerular basement membranelamininpodocytestype IV collagenvascular endothelial growth factor

Identifiers

PMID19568349
PMCPMC2659369
OpenAlexW1994244512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.