Evidence map›Paper›PMID 19568321›Full record

ArticleTetrahedron2007

Effect of extended conjugation with a phenylethynyl group on the fluorescent properties of water-soluble arylboronic acids.

Shi-Long Zheng, Na Lin, Suazette Reid, Binghe Wang

Abstract read
In one paragraph

Article in Tetrahedron, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shi-Long ZhengDepartment of Chemistry and Center for Biotechnology and Drug Design, Georgia State University, Atlanta, GA 30302-4098, USA.
Na Lin
Suazette Reid
Binghe Wang

Funding

Selection of Boronic Acid-modified Aptamers for GlycoproteinsR01GM084933 · NIGMS · GEORGIA STATE UNIVERSITY · PI WANG, BINGHE · 2008 to 2011
$1.2M
FLUORESCENT TAGS TARGETED ON CELL SURFACE CARBOHYDRATESR33CA088343 · NCI · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI WANG, BINGHE · 2002 to 2003
$555k
Fluorescent Aptamers for Glycoprotein DetectionR21CA113917 · NCI · GEORGIA STATE UNIVERSITY · PI WANG, BINGHE · 2005 to 2006
$366k
MRI contrast agents targeting carbohydrate biomarkersR21CA123329 · NCI · GEORGIA STATE UNIVERSITY · PI WANG, BINGHE · 2006 to 2007
$357k
FLUORESCENT TAGS TARGETED ON CELL SURFACE CARBOHYDRATESR21CA088343 · NCI · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI WANG, BINGHE · 2000 to 2001
$288k
NCI NIH HHS R21 CA088343NCI NIH HHS R21 CA113917NCI NIH HHS R21 CA123329NCI NIH HHS R33 CA088343NIGMS NIH HHS R01 GM084933
6 · The paper itself

Abstract

Boronic acids that change fluorescent properties upon sugar binding are very important reporter units for the development of small molecule lectin mimics (boronolectins). Aimed at developing long wavelength fluorescent boronic acid reporter compounds, we have designed and synthesized a series of boronic acid analogs 2a-d with an extended π conjugation. Such designs are based on earlier fluorescent boronic acids that change fluorescent properties upon sugar binding. Compared with the corresponding parent chromophores, these new compounds with extended conjugations show longer excitation and emission wavelengths as designed. The patterns of fluorescent changes for the new compounds are also different from that of the corresponding parent compounds.

Identifiers

PMID19568321
PMCPMC2702878

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.