SynthesisJournal of the American Medical Informatics Association : JAMIA
Does computerized provider order entry reduce prescribing errors for hospital inpatients? A systematic review.
Synthesis in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 15 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
88 citing papers in PubMed, 15 syntheses or guidelines pooled it.
- How effective are electronic medication systems in reducing medication error rates and associated harm among hospital inpatients? A systematic review and meta-analysis.Journal of the American Medical Informatics Association : JAMIA · 2021Pooled it
- The impact of health information technology on prescribing errors in hospitals: a systematic review and behaviour change technique analysis.Systematic reviews · 2020Pooled it
- Improving Patients' Medication Adherence and Outcomes in Nonhospital Settings Through eHealth: Systematic Review of Randomized Controlled Trials.Journal of medical Internet research · 2020Pooled it
- A systematic review of the impact of health information technology on nurses' time.Journal of the American Medical Informatics Association : JAMIA · 2020Pooled it
- Manually-generated reminders delivered on paper: effects on professional practice and patient outcomes.The Cochrane database of systematic reviews · 2019Pooled it
- Prevalence of Medication Errors Among Paediatric Inpatients: Systematic Review and Meta-Analysis.Drug safety · 2019Pooled it
- Effect of Electronic Prescribing Strategies on Medication Error and Harm in Hospital: a Systematic Review and Meta-analysis.Journal of general internal medicine · 2019Pooled it
- Factors contributing to medication errors made when using computerized order entry in pediatrics: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2018Pooled it
- Impact of commercial computerized provider order entry (CPOE) and clinical decision support systems (CDSSs) on medication errors, length of stay, and mortality in intensive care units: a systematic review and meta-analysis.Journal of the American Medical Informatics Association : JAMIA · 2017Pooled it
- Information Technology-Based Interventions to Improve Drug-Drug Interaction Outcomes: A Systematic Review on Features and Effects.Journal of medical systems · 2017Pooled it
- The effectiveness of computerized order entry at reducing preventable adverse drug events and medication errors in hospital settings: a systematic review and meta-analysis.Systematic reviews · 2014Pooled it
- Causes of medication administration errors in hospitals: a systematic review of quantitative and qualitative evidence.Drug safety · 2013Pooled it
- The impact of eHealth on the quality and safety of health care: a systematic overview.PLoS medicine · 2011Pooled it
- The impact of the electronic medical record on structure, process, and outcomes within primary care: a systematic review of the evidence.Journal of the American Medical Informatics Association : JAMIAPooled it
- Barriers and facilitators to implementing electronic prescription: a systematic review of user groups' perceptions.Journal of the American Medical Informatics Association : JAMIAPooled it
- Understanding and preventing wrong-patient electronic orders: a randomized controlled trial.Journal of the American Medical Informatics Association : JAMIATrial
- Patterns and Determinants of Medication Errors Across the Medication-Use Process:Saudi medical journal · 2026Observational
- Resolution rate of prescribing errors after advice from a specialised hospital pharmacist or a substitute hospital pharmacist: a retrospective cross-sectional study.European journal of hospital pharmacy : science and practice · 2026Article
- Evaluation of a hospital-based opioid stewardship program on high-risk opioid prescribing in a Canadian setting: an interrupted time series analysis.Addiction science & clinical practice · 2025Article
- Risk Management and Patient Safety in the Artificial Intelligence Era: A Systematic Review.Healthcare (Basel, Switzerland) · 2024Review
28 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous reviews have examined evidence of the impact of CPOE on medication errors, but have used highly variable definitions of "error". We attempted to answer a very focused question, namely, what evidence exists that CPOE systems reduce prescribing errors among hospital inpatients? We identified 13 papers (reporting 12 studies) published between 1998 and 2007. Nine demonstrated a significant reduction in prescribing error rates for all or some drug types. Few studies examined changes in error severity, but minor errors were most often reported as decreasing. Several studies reported increases in the rate of duplicate orders and failures to discontinue drugs, often attributed to inappropriate selection from a dropdown menu or to an inability to view all active medication orders concurrently. The evidence-base reporting the effectiveness of CPOE to reduce prescribing errors is not compelling and is limited by modest study sample sizes and designs. Future studies should include larger samples including multiple sites, controlled study designs, and standardized error and severity reporting. The role of decision support in minimizing severe prescribing error rates also requires investigation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.