Evidence map›Paper›PMID 19564845›Full record

ArticleNature methods2009

Limitations and possibilities of small RNA digital gene expression profiling.

Sam E V Linsen, Elzo de Wit, Georges Janssens, Sheila Heater, Laura Chapman, Rachael K Parkin, Brian Fritz, Stacia K Wyman, Ewart de Bruijn, Emile E Voest and 3 more

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Nature methods, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 167 papers.

0numbers the graph read from it
0cells of the map it votes in
167citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

167 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Interpreting ribosome dynamics during mRNA translation.The Journal of biological chemistry · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Analysis of MicroRNAs in Ferroptosis.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  13. APE1 controls DICER1 expression in NSCLC through miR-33a and miR-130b.Cellular and molecular life sciences : CMLS · 2022
    Article
  14. Review
  15. Review
  16. Article
  17. The MicroRNA Family Gets Wider: The IsomiRs Classification and Role.Frontiers in cell and developmental biology · 2021
    Review
  18. Article
  19. Article
  20. Article

107 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sam E V Linsen
Elzo de Wit
Georges Janssens
Sheila Heater
Laura Chapman
Rachael K Parkin
Brian Fritz
Stacia K Wyman
Ewart de Bruijn
Emile E Voest
Scott Kuersten
Muneesh Tewari
Edwin Cuppen

Funding

TRANSCRIPTOME AND PROTEOME STRATIFICATION OF PROSTATE ADENOCARCINOMA PHENOTYPESP50CA097186 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI John Kyung Lee · 2002 to 2026
$58.1M
CORE--VECTOR PRODUCTIONP30DK056465 · NIDDK · FRED HUTCHINSON CANCER RESEARCH CENTER · PI HEIMFELD, SHELLY · 1999 to 2014
$14.9M
NCI NIH HHS P50 CA097186NCI NIH HHS P50 CA97186NIDDK NIH HHS P30 DK56465
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsDatabases, Nucleic AcidGene Expression ProfilingGene LibraryMicroRNAsRatsMicroRNAs

Identifiers

PMID19564845

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.