Evidence map›Paper›PMID 19564550›Full record

ReviewHypertension (Dallas, Tex. : 1979)2009

Thiazide effects and adverse effects: insights from molecular genetics.

David H Ellison, Johannes Loffing

Registry-linked trialAbstract readReview
In one paragraph

Review in Hypertension (Dallas, Tex. : 1979), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02497742 (Once Versus Twice Daily Electrolyte Monitoring in CHF; a Study Monitoring Electrolytes in Congestive Heart Failure Patients Being Actively Diuresed in Hospital), which is not on this map. Cited by 67 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02497742 nacompletednot on this mapstarted 2015, after this paper: background citation

Once Versus Twice Daily Electrolyte Monitoring in CHF; a Study Monitoring Electrolytes in Congestive Heart Failure Patients Being Actively Diuresed in Hospital

TypeinterventionalSponsorVanderbilt UniversityRan2015 to 2017Enrolled96ConditionsHeart FailureArmsBasic metabolic panel
3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Thiazide diuretic usage and risk of fracture: a meta-analysis of cohort studies.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Pooled it
  4. Pooled it
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Aging and sex differences in salt sensitivity of blood pressure.Clinical science (London, England : 1979) · 2025
    Review
  14. Review
  15. Pendrin: linking acid base to blood pressure.Pflugers Archiv : European journal of physiology · 2024
    Review
  16. Review
  17. The role of NaPflugers Archiv : European journal of physiology · 2024
    Review
  18. Article
  19. The role ofJournal of pharmaceutical analysis · 2023
    Review
  20. Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

David H EllisonDivision of Nephrology and Hypertension, Oregon Health & Science University, 3314 SW US Veterans Hospital Rd, Portland, OR 97239, USA. ellisond@ohsu.edu
Johannes Loffing

Funding

WNK Kinase Regulation of Thiazide-sensitive NaCl TransportR01DK051496 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI David Hoadley Ellison, CHAO-LING YANG · 1998 to 2026
$8.4M
NIDDK NIH HHS DK51496NIDDK NIH HHS R01 DK051496
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBlood Pressure DeterminationFemaleGlomerular Filtration RateHumansHyperglycemiaHypertensionHypokalemiaKidney DiseasesMaleMolecular BiologyPrognosisRatsRisk AssessmentSensitivity and SpecificitySeverity of Illness IndexThiazides

Identifiers

PMID19564550
PMCPMC2753383

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.