Evidence map›Paper›PMID 19564303›Full record

Trial reportPediatrics2009

Sleep-disordered breathing and behaviors of inner-city children with asthma.

Maria Fagnano, Edwin van Wijngaarden, Heidi V Connolly, Margaret A Carno, Emma Forbes-Jones, Jill S Halterman

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Pediatrics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01175369 (School-Based Asthma Therapy), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01175369 nacompletednot on this map

School-Based Asthma Therapy: Stage 2 Effectiveness Study

TypeinterventionalSponsorUniversity of RochesterRan2006 to 2012Enrolled530ConditionsAsthmaArmsSchool-based Care
3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Associations of Snoring and Asthma Morbidity in the School Inner-City Asthma Study.The journal of allergy and clinical immunology. In practice · 2021
    Article
  3. Article
  4. Article
  5. Asthma and subjective sleep disordered breathing in a large cohort of urban adolescents.The Journal of asthma : official journal of the Association for the Care of Asthma · 2017
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Eczema, sleep, and behavior in children.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2010
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria FagnanoDepartment of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA. maria_fagnano@urmc.rochester.edu
Edwin van Wijngaarden
Heidi V Connolly
Margaret A Carno
Emma Forbes-Jones
Jill S Halterman

Funding

School-Based Telemedicine Enhanced Asthma Management (SB-TEAM)R01HL079954 · NHLBI · UNIVERSITY OF ROCHESTER · PI HALTERMAN, JILL S · 2006 to 2016
$6.6M
NHLBI NIH HHS R01 HL079954NHLBI NIH HHS R01-HL079954
6 · The paper itself

Abstract

objectiveTo explore the relationship between sleep-disordered breathing (SDB) and behavioral problems among inner-city children with asthma.

methodsWe examined data for 194 children (aged 4-10 years) who were enrolled in a school-based asthma intervention program (response rate: 72%). SDB was assessed by using the Sleep-Related Breathing Disorder Questionnaire that contains 3 subscales: snoring, sleepiness, and attention/hyperactivity. For the current study, we modified the Sleep-Related Breathing Disorder Questionnaire by removing the 6 attention/hyperactivity items. A sleep score of >0.33 was considered indicative of SDB. To assess behavior, caregivers completed the Behavior Problem Index (BPI), which includes 8 behavioral subdomains. We conducted bivariate analyses and multiple linear regression to determine the association of SDB with BPI scores.

resultsThe majority of children (mean age: 8.2 years) were male (56%), black (66%), and insured by Medicaid (73%). Overall, 33% of the children experienced SDB. In bivariate analyses, children with SDB had significantly higher (worse) behavior scores compared with children without SDB on total BPI (13.7 vs 8.8) and the subdomains externalizing (9.4 vs 6.3), internalizing (4.4 vs 2.5), anxious/depressed (2.4 vs 1.3), headstrong (3.2 vs 2.1), antisocial (2.3 vs 1.7), hyperactive (3.0 vs 1.8), peer conflict (0.74 vs 0.43), and immature (2.0 vs 1.5). In multiple regression models adjusting for several important covariates, SDB remained significantly associated with total BPI scores and externalizing, internalizing, anxious/depressed, headstrong, and hyperactive behaviors. Results were consistent across SDB subscales (snoring, sleepiness).

conclusionsWe found that poor sleep was independently associated with behavior problems in a large proportion of urban children with asthma. Systematic screening for SDB in this high-risk population might help to identify children who would benefit from additional intervention.

Indexed as

ChildChild Behavior DisordersChild, PreschoolComorbidityCross-Sectional StudiesFemaleHumansMaleNew YorkSleep Apnea SyndromesUrban Population

Identifiers

PMID19564303
PMCPMC2704979

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.