ReviewClinical reviews in allergy & immunology2010
Antiphospholipid antibody-mediated reproductive failure in antiphospholipid syndrome.
Review in Clinical reviews in allergy & immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Glucocorticoids Improve the Pregnancy Rate and Outcome in Women With Unexplained Positive Autoantibodies: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2022Pooled it
- Irreversible vision loss in antiphospholipid syndrome complicated by pre-eclampsia: a case presentation and literature review.BMC pregnancy and childbirth · 2025Review
- Cluster analysis of antiphospholipid antibodies-associated adverse pregnancy outcome patients: based on a 13-years cohort study.Clinical and experimental medicine · 2023Article
- Pregnancy Outcome in Women with Obstetric and Thrombotic Antiphospholipid Syndrome-A Retrospective Analysis and a Review of Additional Treatment in Pregnancy.Clinical reviews in allergy & immunology · 2017Article
- ApoE Receptor 2 Mediation of Trophoblast Dysfunction and Pregnancy Complications Induced by Antiphospholipid Antibodies in Mice.Arthritis & rheumatology (Hoboken, N.J.) · 2016Article
- Anti-Phosphatidylserine/Prothrombin Antibodies Are Associated with Adverse Pregnancy Outcomes.Journal of immunology research · 2015Article
- The autoimmune side of heart and lung diseases.Clinical reviews in allergy & immunology · 2013Review
- Bilateral sudden hearing loss following habitual abortion: a case report and review of literature.International journal of clinical and experimental medicine · 2013Article
- The future of autoimmunity.Clinical reviews in allergy & immunology · 2012Article
- Mechanisms and pathophysiology of autoimmune disease.Clinical reviews in allergy & immunology · 2012Article
- Loss of maternal annexin A5 increases the likelihood of placental platelet thrombosis and foetal loss.Scientific reports · 2012Article
- Cutting-edge issues in organ-specific autoimmunity.Clinical reviews in allergy & immunology · 2011Article
- Role of tissue factor in the maternal immunological attack of the embryo in the antiphospholipid syndrome.Clinical reviews in allergy & immunology · 2010Review
- Serum Protein Profile in Women With Pregnancy Morbidity Associated With Antiphospholipid Syndrome.Journal of human reproductive sciencesArticle
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The association of elevated titers of circulating antiphospholipid (anti-PL) Abs in antiphospholipid syndrome (APS) and reproductive failure is well established in the literature. The clinical features include recurrent abortions at various stages, including implantation, placentation in the first trimester, miscarriages in the second and third trimesters, intrauterine growth retardation, preeclampsia with placental insufficiency and growth restrictions, arterial and venous thrombosis, and possibly also infertility. APS-mediated recurrent pregnancy loss and other features of reproductive failure might result from diverse autoimmune factors, inflammation, involving different mechanisms, which encompass pathogenic anti-PL Abs. Herein, we discuss the association of anti-PL Abs with reproductive failure with special emphasis on antiphospholipid autoantibodies characterizing APS. This association is evident from either human studies or murine models.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.