Trial reportSurgery today2009
Aloe versus silver sulfadiazine creams for second-degree burns: a randomized controlled study.
Trial report in Surgery today, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Herbal Medicine for the Management of Wounds: A Systematic Review of Clinical Studies.Infectious disorders drug targets · 2025Pooled it
- Antiseptics for burns.The Cochrane database of systematic reviews · 2017Pooled it
- Antibiotic prophylaxis for preventing burn wound infection.The Cochrane database of systematic reviews · 2013Pooled it
- Aloe vera for treating acute and chronic wounds.The Cochrane database of systematic reviews · 2012Pooled it
- Prevention of acute radiation-induced Proctitis by Aloe vera: a prospective randomized, double-blind, placebo controlled clinical trial in Pelvic Cancer patients.BMC complementary medicine and therapies · 2020Trial
- Trial
- Article
- Hormesis: induction byOpen medicine (Warsaw, Poland) · 2026Review
- Current State and Advances in Antimicrobial Strategies for Burn Wound Dressings: From Metal-Based Antimicrobials and Natural Bioactive Agents to Future Perspectives.International journal of molecular sciences · 2025Review
- Production ofLife (Basel, Switzerland) · 2025Article
- An Overview of Recent Developments in the Management of Burn Injuries.International journal of molecular sciences · 2023Review
- Current and Future Developments in Wound Healing.Facial plastic surgery : FPS · 2023Article
- Review
- Evidence for Natural Products as Alternative Wound-Healing Therapies.Biomolecules · 2023Review
- The Potential of Medicinal Plants and Natural Products in the Treatment of Burns and Sunburn-A Review.Pharmaceutics · 2023Review
- Silver Nanoparticles Phytofabricated throughAntibiotics (Basel, Switzerland) · 2023Article
- A Systematic Review and Meta-Analysis Comparing Burn Healing Outcomes Between Silver Sulfadiazine and Aloe vera.Cureus · 2022Review
- Hydrogels for the management of second-degree burns: currently available options and future promise.Burns & trauma · 2022Review
- The effects of oralHeliyon · 2021Article
- Polymer-Based Scaffolds Loaded withPharmaceutics · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeBurn injury is associated with a high incidence of death and disability; yet its management remains problematic and costly. We conducted this clinical study to evaluate the efficacy of aloe vera cream for partial thickness burn wounds and compare its results with those of silver sulfadiazine (SSD).
methodsThirty patients with similar types of second-degree burns at two sites on different parts of the body were included in this study. Each patient had one burn treated with topical SSD and one treated with aloe cream, randomly.
resultsThe rate of re-epithelialization and healing of the partial thickness burns was significantly faster in the site treated with aloe than in the site treated with SSD (15.9 +/- 2 vs 18.73 +/- 2.65 days, respectively; P < 0.0001). The sites treated with aloe were completely healed in less than 16 days vs 19 days for the sites treated with SSD.
conclusionThese results clearly demonstrated the greater efficacy of aloe cream over SSD cream for treating second-degree burns.
Indexed as
Identifiers
19562446What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.