GuidelineEuropean journal of nuclear medicine and molecular imaging2009
EANM guidelines for ventilation/perfusion scintigraphy : Part 1. Pulmonary imaging with ventilation/perfusion single photon emission tomography.
Guideline in European journal of nuclear medicine and molecular imaging, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
98 citing papers in PubMed, 3 syntheses or guidelines pooled it, 346 citations in OpenAlex.
- Imaging for the exclusion of pulmonary embolism in pregnancy.The Cochrane database of systematic reviews · 2017Pooled it
- The essence of the Japan Radiological Society/Japanese College of Radiology Imaging Guideline.Japanese journal of radiology · 2016Guideline
- EANM guidelines for ventilation/perfusion scintigraphy : Part 2. Algorithms and clinical considerations for diagnosis of pulmonary emboli with V/P(SPECT) and MDCT.European journal of nuclear medicine and molecular imaging · 2009Guideline
- Comparison of three diagnostic strategies for suspicion of pulmonary embolism: planar ventilation/perfusion scan, CT pulmonary angiography and single-photon emission CT ventilation/perfusion scan - a multicentre, non-inferiority randomised controlled trial.The European respiratory journal · 2026Trial
- Ventilation/perfusion SPECT in chronic obstructive pulmonary disease: an evaluation by reference to symptoms, spirometric lung function and emphysema, as assessed with HRCT.European journal of nuclear medicine and molecular imaging · 2011Trial
- Functional alterations due to post-COVID-19 lung lesions - lessons from a multicenter V/Q SPECT/CT based registry.European journal of nuclear medicine and molecular imaging · 2026Article
- Advancements in Targeted Radiopharmaceuticals: Innovations in Diagnosis and Therapy for Enhanced Cancer Management.Chembiochem : a European journal of chemical biology · 2026Review
- Stress Echocardiography to Detect Exercise Pulmonary Hypertension in Patients With Chronic Thromboembolic Pulmonary Disease.Pulmonary medicine · 2026Observational
- Scintigraphic Assessment of Lung Perfusion and Ventilation in Patients After Pneumonectomy.Journal of clinical medicine · 2025Article
- The clinical utility of ventilation-perfusion scintigraphy in the classification of pulmonary hypertension.Japanese journal of radiology · 2025Review
- The Predictive Value of Quantitative Analysis of SPECT V/Q Imaging for Postoperative Persistent/Recurrent Pulmonary Hypertension in Patients With Chronic Thromboembolic Pulmonary Hypertension After Pulmonary Endarterectomy.Pulmonary circulation · 2025Article
- Perfusion estimation from dynamic non-contrast computed tomography using self-supervised learning and a physics-inspired U-net transformer architecture.International journal of computer assisted radiology and surgery · 2025Article
- On the construction of a large-scale database of AI-assisted annotating lung ventilation-perfusion scintigraphy for pulmonary embolism (VQ4PEDB).Frontiers in nuclear medicine · 2025Article
- Advances in Aerosol Formulation for Targeted Delivery of Therapeutic Agents from Nose to Brain.Current drug delivery · 2025Review
- Improved detection of small pulmonary embolism on unenhanced computed tomography using an artificial intelligence-based algorithm - a single centre retrospective study.The international journal of cardiovascular imaging · 2024Article
- Validation of a radiosynthesis method and a novel quality control system for [EJNMMI radiopharmacy and chemistry · 2024Article
- Exercise pulmonary hypertension in chronic thromboembolic pulmonary disease: A right heart catheterization study.Pulmonary circulation · 2024Article
- Article
- A Study of CT-derived Radiation Dose Calculation in Lung Q-SPECT/CT Imaging.Molecular imaging and radionuclide therapy · 2023Article
- Clot Burden As a Predictor of Chronic Thromboembolic Pulmonary Hypertension After Acute Pulmonary Embolism: A Cohort Study.Thoracic research and practice · 2023Article
38 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pulmonary embolism (PE) can only be diagnosed with imaging techniques, which in practice is performed using ventilation/perfusion scintigraphy (V/P(SCAN)) or multidetector computed tomography of the pulmonary arteries (MDCT). The epidemiology, natural history, pathophysiology and clinical presentation of PE are briefly reviewed. The primary objective of Part 1 of the Task Group's report was to develop a methodological approach to and interpretation criteria for PE. The basic principle for the diagnosis of PE based upon V/P(SCAN) is to recognize lung segments or subsegments without perfusion but preserved ventilation, i.e. mismatch. Ventilation studies are in general performed after inhalation of Krypton or technetium-labelled aerosol of diethylene triamine pentaacetic acid (DTPA) or Technegas. Perfusion studies are performed after intravenous injection of macroaggregated human albumin. Radiation exposure using documented isotope doses is 1.2-2 mSv. Planar and tomographic techniques (V/P(PLANAR) and V/P(SPECT)) are analysed. V/P(SPECT) has higher sensitivity and specificity than V/P(PLANAR). The interpretation of either V/P(PLANAR) or V/P(SPECT) should follow holistic principles rather than obsolete probabilistic rules. PE should be reported when mismatch of more than one subsegment is found. For the diagnosis of chronic PE, V/P(SCAN) is of value. The additional diagnostic yield from V/P(SCAN) includes chronic obstructive lung disease (COPD), heart failure and pneumonia. Pitfalls in V/P(SCAN) interpretation are considered. V/P(SPECT) is strongly preferred to V/P(PLANAR) as the former permits the accurate diagnosis of PE even in the presence of comorbid diseases such as COPD and pneumonia. Technegas is preferred to DTPA in patients with COPD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.