SynthesisWiener klinische Wochenschrift2009
Neurohormonal activation and inflammation in chronic cardiopulmonary disease: a brief systematic review.
Synthesis in Wiener klinische Wochenschrift, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 27 citations in OpenAlex.
- Thymopentin improves cardiac function in older patients with chronic heart failure.Anatolian journal of cardiology · 2017Trial
- THE RENIN-ANGIOTENSIN SYSTEM AND THE BIOLOGY OF SKELETAL MUSCLE: MECHANISMS OF MUSCLE WASTING IN CHRONIC DISEASE STATES.Transactions of the American Clinical and Climatological Association · 2016Article
- No association between exacerbation frequency and stroke in patients with COPD.International journal of chronic obstructive pulmonary disease · 2016Article
- Mechanisms of Cachexia in Chronic Disease States.The American journal of the medical sciences · 2015Article
- Molecular mechanisms and signaling pathways of angiotensin II-induced muscle wasting: potential therapeutic targets for cardiac cachexia.The international journal of biochemistry & cell biology · 2013Review
- Non-invasive assessment of cardiac hemodynamics in patients with advanced cancer and with chronic heart failure: a pilot feasibility study.Archives of medical science : AMS · 2013Article
- Short-term outcomes in heart failure patients with chronic obstructive pulmonary disease in the community.World journal of cardiology · 2012Article
- Body mass index and prognosis in patients hospitalized with acute exacerbation of chronic obstructive pulmonary disease.Journal of cachexia, sarcopenia and muscle · 2011Article
- Feasibility of transcutaneous electrical muscle stimulation in acute exacerbation of COPD.Wiener klinische Wochenschrift · 2011Article
- Heart failure and chronic obstructive pulmonary disease: Two for tea or tea for two?World journal of cardiology · 2010Article
- COPD is not COPD is not allergy.Wiener klinische Wochenschrift · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic cardiopulmonary disease typically induces and maintains (over)activation of several phylogenetically old adaptational and defensive mechanisms. Activation was usually needed for a limited period during acute danger or injury. In chronic disease conditions, however, those mechanisms are kept activated for longer periods. Eventually, irreversible damage is done and this contributes to impaired function and worse prognosis in a variety of chronic disease. Landmark trials in chronic heart failure have provided robust evidence for prognostic benefit for neurohormonal antagonists. Retrospective and epidemiological data for their beneficial effect in chronic obstructive pulmonary disease begin to accumulate and new fields (e.g. cancer and stroke) could be pending in the future.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.