ReviewNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2009
Pediatric brain tumors: current treatment strategies and future therapeutic approaches.
Review in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
76 citing papers in PubMed, 5 syntheses or guidelines pooled it, 170 citations in OpenAlex.
- Symptomatic cerebral vasospasm after posterior fossa surgery in pediatric patients: single-center study and systematic literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Pooled it
- Late effects of high-dose methotrexate treatment in childhood cancer survivors-a systematic review.BMC cancer · 2022Pooled it
- Childhood Brain Tumors: a Systematic Review of the Structural Neuroimaging Literature.Neuropsychology review · 2017Pooled it
- A systematic review of neuropsychological outcomes following posterior fossa tumor surgery in children.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015Pooled it
- Pooled it
- Assessing 'second-look' tumour resectability in childhood posterior fossa ependymoma-a centralised review panel and staging tool for future studies.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016Trial
- Modeling medulloblastoma pathogenesis and treatment in human cerebellar organoids.Genes & development · 2026Article
- Validating Brain Tumor Reporting and Data System (BT-RADS) as a Diagnostic Tool for Glioma Follow-Up after Surgery.Biomedicines · 2024Article
- An Update on Emergent Nano-Therapeutic Strategies against Pediatric Brain Tumors.Brain sciences · 2024Review
- New CNS tumor classification: The importance in pediatric neurosurgical practice.Surgical neurology international · 2024Review
- Immunotherapy for Pediatric Brain and Spine Tumors: Current State and Future Directions.Pediatric neurosurgery · 2023Review
- Role of Circular RNA in Brain Tumor Development.Cells · 2022Review
- Essential Management of Pediatric Brain Tumors.Children (Basel, Switzerland) · 2022Review
- Nanoparticles for Diagnosis and Target Therapy in Pediatric Brain Cancers.Diagnostics (Basel, Switzerland) · 2022Review
- The tentative application of en bloc concept in the pediatric brain tumor: Experience from a large pediatric center in china.Frontiers in oncology · 2022Article
- The epidemiology of primary and metastatic brain tumors in infancy through childhood.Journal of neuro-oncology · 2022Article
- Defining and timing of palliative opportunities in children with central nervous system tumors.Neuro-oncology practice · 2021Article
- Review
- Epidemiology and prognostic factors of pediatric brain tumor survival in the US: Evidence from four decades of population data.Cancer epidemiology · 2021Article
- Inositol treatment inhibits medulloblastoma through suppression of epigenetic-driven metabolic adaptation.Nature communications · 2021Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pediatric CNS tumors are the most common solid tumors of childhood and the second most common cancer after hematological malignancies accounting for approximate 20 to 25% of all primary pediatric tumors. With over 3,000 new cases per year in the United States, childhood CNS tumors are the leading cause of death related to cancer in this population. The prognosis for these patients has improved over the last few decades, but current therapies continue to carry a high risk of significant side effects, especially for the very young. Currently a combination of surgery, radiation, and chemotherapy is often used in children greater than 3 years of age. This article will outline current and future therapeutic strategies for the most common pediatric CNS tumors, including primitive neuroectodermal tumors such as medulloblastoma, as well as astrocytomas and ependymomas.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.