Evidence map›Paper›PMID 19560047›Full record

ReviewSeminars in cell & developmental biology2009

Cellular events in nicotine addiction.

Rachel E Penton, Robin A J Lester

Abstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Trial
  3. A history of addiction through the six editions of Kandel'sFrontiers in behavioral neuroscience · 2026
    Review
  4. Article
  5. Review
  6. Nicotine Addiction: Neurobiology and Mechanism.Journal of pharmacopuncture · 2020
    Review
  7. Article
  8. Cognitive Effects of Nicotine: Recent Progress.Current neuropharmacology · 2018
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rachel E PentonDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. rpenton@nrc.uab.edu
Robin A J Lester

Funding

SUBUNIT SPECIFIC REGULATION OF NICOTINIC RECEPTORSR01DA011940 · NIDA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LESTER, ROBIN A · 1998 to 2008
$1.6M
NIDA NIH HHS DA11940NIDA NIH HHS R01 DA011940
6 · The paper itself

Abstract

In the 25 years since the observation that chronic exposure to nicotine could regulate the number and function of high affinity nicotine binding sites in the brain there has been a major effort to link alterations in nicotinic acetylcholine receptors (nAChRs) to nicotine-induced behaviors that drive the addiction to tobacco products. Here we review the proposed roles of various nAChR subtypes in the addiction process, with emphasis on how they are regulated by nicotine and the implications for understanding the cellular neurobiology of addiction to this drug.

Indexed as

BehaviorHumansNicotineReceptors, NicotinicTobacco Use DisorderNicotineReceptors, Nicotinic

Identifiers

PMID19560047
PMCPMC2704462

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.