ReviewThe International journal of developmental biology2009
Pattern formation today.
Review in The International journal of developmental biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Structural causes of pattern formation and loss through model-independent bifurcation analysis.Journal of mathematical biology · 2025Article
- Review
- Spatiotemporal Patterning Enabled by Gene Regulatory Networks.ACS omega · 2023Article
- Self-organization process in newborn skin organoid formation inspires strategy to restore hair regeneration of adult cells.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Deciphering principles of morphogenesis from temporal and spatial patterns on the integument.Developmental dynamics : an official publication of the American Association of Anatomists · 2015Article
- p53/p63/p73 in the epidermis in health and disease.Cold Spring Harbor perspectives in medicine · 2014Review
- Topology of feather melanocyte progenitor niche allows complex pigment patterns to emerge.Science (New York, N.Y.) · 2013Article
- Strong inter-population cooperation leads to partner intermixing in microbial communities.eLife · 2013Article
- Review
- Brain basis of self: self-organization and lessons from dreaming.Frontiers in psychology · 2013Article
- Patterning skin by planar cell polarity: the multi-talented hair designer.Experimental dermatology · 2012Article
- Self-organizing and stochastic behaviors during the regeneration of hair stem cells.Science (New York, N.Y.) · 2011Article
- In search of the Golden Fleece: unraveling principles of morphogenesis by studying the integrative biology of skin appendages.Integrative biology : quantitative biosciences from nano to macro · 2011Article
- Regenerative patterning in Swarm Robots: mutual benefits of research in robotics and stem cell biology.The International journal of developmental biology · 2009Article
- Module-based complexity formation: periodic patterning in feathers and hairs.Wiley interdisciplinary reviews. Developmental biologyReview
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Authors and funding
2 authors.
Funding
Abstract
Patterns are orders embedded in randomness. They may appear as spatial arrangements or temporal series, and the elements may appear identical or with variations. Patterns exist in the physical world as well as in living systems. In the biological world, patterns can range from simple to complex, forming the basic building blocks of life. The process which generates this ordering in the biological world was termed pattern formation. Since Wolpert promoted this concept four decades ago, scientists from molecular biology, developmental biology, stem cell biology, tissue engineering, theoretical modeling and other disciplines have made remarkable progress towards understanding its mechanisms. It is time to review and re-integrate our understanding. Here, we explore the origin of pattern formation, how the genetic code is translated into biological form, and how complex phenotypes are selected over evolutionary time. We present four topics: Principles, Evolution, Development, and Stem Cells and Regeneration. We have interviewed several leaders in the field to gain insight into how their research and the field of pattern formation have shaped each other. We have learned that both molecular process and physico-chemical principles are important for biological pattern formation. New understanding will emerge through integration of the analytical approach of molecular-genetic manipulation and the systemic approach of model simulation. We regret that we could not include every major investigator in the field, but hope that this Special Issue of the Int. J. Dev. Biol. represents a sample of our knowledge of pattern formation today, which will help to stimulate more research on this fundamental process.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.