Evidence map›Paper›PMID 19557500›Full record

ArticleJournal of neuro-oncology2009

Evaluation of neo-angiogenesis in a case of chordoid meningioma.

Valeria Barresi, Giovanni Tuccari

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Journal of neuro-oncology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Chordoid meningioma: a retrospective series of seven consecutive cases.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2013
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Valeria BarresiDepartment of Human Pathology, University of Messina, Messina, Italy. vbarresi@unime.it.
Giovanni TuccariDepartment of Human Pathology, University of Messina, Messina, Italy.
Azienda Ospedaliera Universitaria Policlinico "G. Martino" · ITUniversity of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chordoid is a rare variant of meningioma that displays a high recurrence rate. In this study we evaluated the immunohistochemical expression of factors that regulate the neo-angiogenesis process in a case of chordoid meningioma with an adverse clinical course. A high microvessel density (MVD), as well as high VEGF and VEGF-R1 expression, was encountered in this tumor. By contrast, the anti-angiogenic factor semaphorin3A, highly expressed in this chordoid meningioma, was ineffective because of the absence of its receptor neuropilin-1. We suggest that VEGF expression and MVD may represent significant prognostic factors in chordoid meningiomas.

Indexed as

AgedAntigens, CDBiopsyEndoglinFatal OutcomeHumansMaleMeningeal NeoplasmsMeningiomaNeovascularization, PathologicNeuropilin-1PrognosisReceptors, Cell SurfaceSemaphorin-3AVascular Endothelial Growth Factor AAntigens, CDEndoglinENG protein, humanNeuropilin-1Receptors, Cell SurfaceSEMA3A protein, humanSemaphorin-3AVascular Endothelial Growth Factor AVEGFA protein, human

Identifiers

PMID19557500
OpenAlexW2074640737

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.