Evidence map›Paper›PMID 19557421›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2009

Intraventricular and subarachnoid basal cisterns neurocysticercosis: a comparative study between traditional treatment versus neuroendoscopic surgery.

Jefferson V Proaño, Jaime Torres-Corzo, Roberto Rodríguez-Della Vecchia, Gabriel Guizar-Sahagun, Leonardo Rangel-Castilla

Registry-linked trialAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04706819 (Clinical, Laboratory and Imaging Features, Treatment Trends and Long Term Outcomes in Patients With Parenchymal and Extraparenchymal Neurocysticercosis-A Registry Based Study), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04706819 unknown statusnot on this mapstarted 2021, after this paper: background citation

Clinical, Laboratory and Imaging Features, Treatment Trends and Long Term Outcomes in Patients With Parenchymal and Extraparenchymal Neurocysticercosis-A Registry Based Study

Typeobservational_patient_registrySponsorAll India Institute of Medical SciencesRan2021 to 2025Enrolled1,000ConditionsNeurocysticercosis, Tropical Disease, Tenia Solium Infection
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 87 citations in OpenAlex.

  1. Guideline
  2. Guideline
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. CystiHuman: A model of human neurocysticercosis.PLoS computational biology · 2022
    Article
  12. Article
  13. The rolling cyst: migrating intraventricular neurocysticercosis-a case-based update.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020
    Review
  14. Optimal Treatment for Subarachnoid Neurocysticercosis: Closer, but Not There yet.The American journal of tropical medicine and hygiene · 2020
    Article
  15. Article
  16. Article
  17. Article
  18. Taenia crassiceps injection into the subarachnoid space of rats simulates radiological and morphological features of racemose neurocysticercosis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017
    Article
  19. Update on the Diagnosis and Management of Neurocysticercosis.Current infectious disease reports · 2016
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Jefferson V ProañoMedical Research Unit for Neurological Diseases, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Mexican Institute of Social Security, 06720 México, DF, México.
Jaime Torres-Corzo
Roberto Rodríguez-Della Vecchia
Gabriel Guizar-Sahagun
Leonardo Rangel-Castilla
Institute for Scientific and Technological Research · MXCentro Medico Nacional Siglo XXI · MXHospital de Especialidades · MXHouston Methodist · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of this study was to evaluate the efficacy of traditional treatment and minimal invasive flexible endoscopy surgery (MIFNES) in the treatment of intraventricular and subarachnoid basal cisterns neurocysticercosis (NCC).

methodsThis was an observational comparative study of two independent series with a total of 140 patients with extremely severe forms of NCC from two different institutions. All 83 patients submitted for traditional treatment series received albendazole, and some of them received additionally praziquantel. Each cycle of both regimens lasted 4 weeks. The majority of these patients had at least one ventriculoperitoneal (VP) shunt. The rest 57 patients were submitted to the MIFNES treatment. The follow-up period was at least 6 months.

resultsIn all patients of both series cysticercal cysts disappeared, became calcified, or were removed. Symptoms of 136 patients improved. Four patients died. The average in the quality of life measured using the Karnofsky scale improved from a mean of 52.22 and 52.44 at the beginning to 85.48 and 90.37 at 6 months (p < 0.003), in the traditional treatment and MIFNES series, respectively. From traditional treatment, almost all patients remained with at least one VP shunt, and from the MIFNES series only 12 patients.

conclusionsThe authors postulate that MIFNES is a good alternative for the management of intraventricular and subarachnoid basal cisterns NCC because it allows removal of most of the parasites, rapid recovery of the patients, and removal and placement of shunt under direct vision when necessary. Traditional treatment is a second option where the MIFNES procedure is not available.

Indexed as

AdolescentAdultAgedAlbendazoleAnthelminticsCerebral VentriclesChildFemaleFollow-Up StudiesHumansMaleMiddle AgedMinimally Invasive Surgical ProceduresNeurocysticercosisNeuroendoscopyPraziquantelAlbendazoleAnthelminticsPraziquantel

Identifiers

PMID19557421
OpenAlexW2039693495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.