Evidence map›Paper›PMID 19557327›Full record

ReviewScience in China. Series C, Life sciences2009

Towards transgenic primates: What can we learn from mouse genetics?

Hui KUANG, Phillip L WANG, Joe Z TSIEN

Abstract readReview
In one paragraph

Review in Science in China. Series C, Life sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Advanced Circuit and Cellular Imaging Methods in Nonhuman Primates.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hui KUANGBrain and Behavior Discovery Institute, School of Medicine, Medical College of Georgia, Augusta, GA 30912, USA.
Phillip L WANG
Joe Z TSIEN

Funding

Hippocampal Network Profiles of Memory AgingR01AG034663 · NIA · AUGUSTA UNIVERSITY · PI TSIEN, JOE Z · 2009 to 2010
$996k
NIA NIH HHS R01 AG034663
6 · The paper itself

Abstract

Considering the great physiological and behavioral similarities with humans, monkeys represent the ideal models not only for the study of complex cognitive behavior but also for the preclinical research and development of novel therapeutics for treating human diseases. Various powerful genetic technologies initially developed for making mouse models are being explored for generating transgenic primate models. We review the latest genetic engineering technologies and discuss the potentials and limitations for systematic production of transgenic primates.

Indexed as

Animals, Genetically ModifiedAnimalsGene Knockout TechniquesHumansMicePrimatesTransgenes

Identifiers

PMID19557327
PMCPMC2969839

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.