ReviewGene2009
The adaptive role of transposable elements in the Drosophila genome.
Review in Gene, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
50 citing papers in PubMed, 96 citations in OpenAlex.
- Transposable elements contribute substantially to naturally occurring genetic lethality in Drosophila melanogaster.PLoS biology · 2026Article
- Arms races between selfish genetic elements and their host defence in termites.Nature communications · 2026Article
- The contribution of transposable element insertions to genetic diversity inbioRxiv : the preprint server for biology · 2025Article
- Lepidopteran Genomes Have Denser Transposable Elements in Smaller Chromosomes, Likely Driven by Non-allelic Homologous Recombination.Genome biology and evolution · 2025Article
- Genetic Variation in Jamaican Populations of the Coffee Berry Borer, Hypothenemus hampei.Genome biology and evolution · 2024Article
- Pathogen infection alters the gene expression landscape of transposable elements in Drosophila melanogaster.G3 (Bethesda, Md.) · 2024Article
- Article
- P-element invasion fuels molecular adaptation in laboratory populations of Drosophila melanogaster.Evolution; international journal of organic evolution · 2023Article
- Effects of Wolbachia on Transposable Element Expression Vary Between Drosophila melanogaster Host Genotypes.Genome biology and evolution · 2023Article
- A novel transposable element-mediated mechanism causes antiviral resistance inProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Article
- Article
- Phenotypic and genotypic parallel evolution in parapatric ecotypes of Senecio.Evolution; international journal of organic evolution · 2021Article
- Transposable Element Mobilization in Interspecific Yeast Hybrids.Genome biology and evolution · 2021Article
- Testing the Genomic Shock Hypothesis Using Transposable Element Expression in Yeast Hybrids.Frontiers in fungal biology · 2021Article
- Article
- Disentangling the determinants of transposable elements dynamics in vertebrate genomes using empirical evidences and simulations.PLoS genetics · 2020Article
- Transposable elements inMobile DNA · 2020Review
- The Role of Sequence Duplication in Transcriptional Regulation and Genome Evolution.Current genomics · 2019Review
- Unprecedented reorganization of holocentric chromosomes provides insights into the enigma of lepidopteran chromosome evolution.Science advances · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Transposable elements (TEs) are short DNA sequences with the capacity to move between different sites in the genome. This ability provides them with the capacity to mutate the genome in many different ways, from subtle regulatory mutations to gross genomic rearrangements. The potential adaptive significance of TEs was recognized by those involved in their initial discovery although it was hotly debated afterwards. For more than two decades, TEs were considered to be intragenomic parasites leading to almost exclusively detrimental effects to the host genome. The sequencing of the Drosophila melanogaster genome provided an unprecedented opportunity to study TEs and led to the identification of the first TE-induced adaptations in this species. These studies were followed by a systematic genome-wide search for adaptive insertions that allowed for the first time to infer that TEs contribute substantially to adaptive evolution. This study also revealed that there are at least twice as many TE-induced adaptations that remain to be identified. To gain a better understanding of the adaptive role of TEs in the genome we clearly need to (i) identify as many adaptive TEs as possible in a range of Drosophila species as well as (ii) carry out in-depth investigations of the effects of adaptive TEs on as many phenotypes as possible.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.