ArticleJournal of materials science. Materials in medicine2009
Characterization of pHEMA-based hydrogels that exhibit light-induced bactericidal effect via release of NO.
Article in Journal of materials science. Materials in medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Novel Antibacterial Hydrogels Incorporating Quaternary Ammonium Monomethacrylate: A Pilot Study on Swelling Behavior and Biological Analysis.Materials (Basel, Switzerland) · 2026Article
- Nitric oxide-releasing PHEMA/polysilsesquioxane photocrosslinked hybrids.RSC advances · 2025Article
- Biological Models for Evaluating Hydrogel-Based Formulations in Wound Healing.Gels (Basel, Switzerland) · 2025Review
- Polymerization of hydroxyethyl methacrylate (HEMA) under rotation to form core-annular hydrogels.Journal of colloid and interface science · 2025Article
- Opportunities for Nitric Oxide in Potentiating Cancer Immunotherapy.Pharmacological reviews · 2022Review
- Recent Advances in Hydrogel-Mediated Nitric Oxide Delivery Systems Targeted for Wound Healing Applications.Pharmaceutics · 2022Review
- pHEMA: An Overview for Biomedical Applications.International journal of molecular sciences · 2021Review
- Synthetic, Natural, and Semisynthetic Polymer Carriers for Controlled Nitric Oxide Release in Dermal Applications: A Review.Polymers · 2021Review
- The evolving landscape for cellular nitric oxide and hydrogen sulfide delivery systems: A new era of customized medications.Biochemical pharmacology · 2020Review
- Providing Antibacterial Activity to Poly(2-Hydroxy Ethyl Methacrylate) by Copolymerization with a Methacrylic Thiazolium Derivative.International journal of molecular sciences · 2018Article
- Antibacterial Hydrogels.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2018Review
- Antimicrobial hydrogels: promising materials for medical application.International journal of nanomedicine · 2018Review
- Advances in the Fabrication of Antimicrobial Hydrogels for Biomedical Applications.Materials (Basel, Switzerland) · 2017Review
- Antimicrobial hydrogels for the treatment of infection.Biopolymers · 2013Review
- Nitric oxide (NO)-induced death of gram-negative bacteria from a light-controlled NO-releasing platform.Chemistry & biodiversity · 2012Article
- Polymer-Based Nitric Oxide Therapies: Recent Insights for Biomedical Applications.Advanced functional materials · 2012Article
- Designed iron carbonyls as carbon monoxide (CO) releasing molecules: rapid CO release and delivery to myoglobin in aqueous buffer, and vasorelaxation of mouse aorta.Inorganic chemistry · 2011Article
- Eradication of Pathogenic Bacteria by Remote Delivery of Nitric Oxide via Light-Triggering of Nitrosyl-Containing Materials.ACS medicinal chemistry letters · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
A light-activated NO donor, [Mn(PaPy(3))(NO)]ClO(4) (1a), has been incorporated into HEMA-based polymer hydrogel and the nitrosyl-polymer conjugate materials 1a(x) · HG and 1a(x) · HG(MB) have been characterized. The NO releasing properties and antibacterial capabilities of these materials in conjunction with growth attenuators such as hydrogen peroxide and methylene blue (MB) are reported. Since the nitrosyl releases NO only upon exposure to light, materials like 1a(x) · HG(MB) could be used as wound dressings that deliver NO under controlled conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.