ReviewThe journal of headache and pain2009
Psychiatric comorbidity in patients with chronic daily headache and migraine: a selective overview including personality traits and suicide risk.
Review in The journal of headache and pain, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 1 synthesis or guideline pooled it, 158 citations in OpenAlex.
- Migraine headache and depression in adults: a systematic Review and Meta-analysis.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2019Pooled it
- Duration and frequency of migraines affect cognitive function: evidence from neuropsychological tests and event-related potentials.The journal of headache and pain · 2017Trial
- Mindfulness and pharmacological prophylaxis after withdrawal from medication overuse in patients with Chronic Migraine: an effectiveness trial with a one-year follow-up.The journal of headache and pain · 2017Trial
- Trial
- Zhengtian Capsule versus flunarizine in patients with migraine: a multi-center, double-blind, double-dummy, randomized controlled, non-inferior clinical trial.BMC complementary and alternative medicine · 2016Trial
- Trial
- Neuroimmune dysregulation and comorbidity mechanisms of major depressive disorder and migraine.BMC psychiatry · 2026Article
- Prognostic Value of Minnesota Multiphasic Personality Inventory-2 (MMPI-2) Profiles in Predicting Outcomes of Occipital Nerve Stimulation for Refractory Chronic Migraine: A Retrospective Bias-Corrected Multivariable Analysis.Current pain and headache reports · 2025Review
- Migraine and major depression: localizing shared genetic susceptibility in different cell types of the nervous systems.Frontiers in neurology · 2023Article
- Efficacy of Onabotulinum Toxin A on Obsessive-Compulsive Traits in a Population of Chronic Migraine Patients.Brain sciences · 2022Article
- Persistence, use of resources and costs in patients under migraine preventive treatment: the PERSEC study.The journal of headache and pain · 2022Observational
- Examining the Interplay of Smartphone Use Disorder, Mental Health, and Physical Symptoms.Frontiers in public health · 2022Article
- Erenumab for the preventive treatment of chronic migraine complicated with medication overuse headache: an observational, retrospective, 12-month real-life study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Observational
- Association between suicidal risks and medication-overuse headache in chronic migraine: a cross-sectional study.The journal of headache and pain · 2021Article
- Demoralization predicts suicidality in patients with cluster headache.The journal of headache and pain · 2021Observational
- Negative effects of accompanying psychiatric disturbances on functionality among adolescents with chronic migraine.BMC neurology · 2021Article
- Migraine: A Review on Its History, Global Epidemiology, Risk Factors, and Comorbidities.Frontiers in neurology · 2021Review
- Regulatory Effects of Acupuncture on Emotional Disorders in Patients With Menstrual Migraine Without Aura: A Resting-State fMRI Study.Frontiers in neuroscience · 2021Article
- Job Satisfaction Mediates the Association between Perceived Disability and Work Productivity in Migraine Headache Patients.International journal of environmental research and public health · 2019Article
- Polygenic risk score: use in migraine research.The journal of headache and pain · 2018Review
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies on the prevalence and impact of psychiatric disorders among headache patients have yielded findings that have clarified the relationship between migraine and major affective disorders, anxiety, illicit drug abuse, nicotine dependence, and suicide attempts. Studies in both clinical and community-based settings have demonstrated an association between migraine and a number of specific psychiatric disorders. In large-scale population-based studies, persons with migraine are from 2.2 to 4.0 times more likely to have depression. In longitudinal studies, the evidence supports a bidirectional relationship between migraine and depression, with each disorder increasing the risk of the other disorder. Although a strong association has been demonstrated consistently for migraine and major depression, especially for migraine with aura, there has been less systematic research on the links between migraine and bipolar disorder. This review will focus on the way in which psychiatric disorders decrease the quality of life and result in a worse prognosis, chronicity of the disease, and a worse response to treatment. Short-term pharmaceutical care intervention improves the patients' mental health, but it does not significantly change the number and severity of headaches. The increase in self-efficacy and mental health associated with pharmaceutical care may be instrumental in improving the long-term pharmacotherapy of patients with migraine and headache.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.