ArticleThe open ophthalmology journal2009
Autoimmune retinopathy in systemic lupus erythematosus: histopathologic features.
Article in The open ophthalmology journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
- Serum epitope-specific anti-recoverin autoantibodies as biomarkers for lupus retinopathy.Arthritis research & therapy · 2026Article
- Diagnosis and treatment of autoimmune retinopathy: review of current approaches.International ophthalmology · 2025Review
- Evaluation of Subclinical Retinal Disease in Patients Affected by Systemic Lupus Erythematosus with No Evidence of Ocular Involvement-An Optical Coherence Tomography Angiography Original Study.Journal of clinical medicine · 2022Article
- Structural Features of Patients with Drusen-like Deposits and Systemic Lupus Erythematosus.Journal of clinical medicine · 2022Article
- Autoantibody profiles and clinical association in Thai patients with autoimmune retinopathy.Scientific reports · 2021Article
- Neurodegeneration in systemic lupus erythematosus: layer by layer retinal study using optical coherence tomography.International journal of retina and vitreous · 2020Article
- Lupus retinopathy: a marker of active systemic lupus erythematosus.Rheumatology international · 2018Article
- Papilloedema and Autoimmune Retinopathy from Systemic Lupus Erythematosus.Neuro-ophthalmology (Aeolus Press) · 2018Article
- Autoimmune Retinopathy: Current Concepts and Practices (An American Ophthalmological Society Thesis).Transactions of the American Ophthalmological Society · 2017Review
- Two mouse models for recoverin-associated autoimmune retinopathy.Molecular vision · 2010Article
- Lupus retinopathy: epidemiology and risk factors.Arquivos brasileiros de oftalmologiaReview
- Rituximab for autoimmune retinopathy: Results of a Phase I/II clinical trial.Taiwan journal of ophthalmologyArticle
- Autoimmune-Related Retinopathy Presenting As Plaquenil Toxicity in Patients With Systemic Lupus Erythematosus.Journal of vitreoretinal diseasesArticle
- Applications of artificial intelligence-assisted retinal imaging in systemic diseases: A literature review.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
- Autoimmune retinopathy associated with systemic lupus erythematosus: A diagnostic dilemma.Taiwan journal of ophthalmologyArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
The ocular pathology of autoimmune retinopathy is demonstrated in a 62-year-old female patient with systemic lupus erythematosus (SLE) who presented with typical clinical autoimmune retinopathy. Macroscopically, there were multiple depigmented lesions in the peripheral retina and choroid and scattered pigmentary bone-spickling at the equator and periphery. Microscopically, there were generalized loss of photoreceptors and thinning of the outer plexiform layer. Many peripheral retinal vessels were sclerotic and occluded, some surrounded by pigment granules and RPE cells. Cobblestone degeneration was prominent in the periphery. Macrophages were seen in the retina, particularly in areas of photoreceptor degeneration. Rare, scattered T- lymphocytes were present in the retina and choroid, while B-cells were notably absent. The optic nerve showed loss of axons and thickened septae. Serum autoantibodies against normal retinal nuclei were detected. These pathological changes represent both known SLE-associated ocular complications as well as possible features of autoimmune retinopathy secondary to SLE.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.