Evidence map›Paper›PMID 19553572›Full record

ArticleJournal of clinical microbiology2009

Evaluation of MeningoFinder, a novel multiplex ligation-dependent probe amplification assay for simultaneous detection of six virus species causing central nervous system infections.

P F G Wolffs, C Vink, J Keijdener, B Habek, M Reijans, G Simons, C A Bruggeman, A J C van den Brule

Open access · greenAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Acute human bocavirus infection in MDS patient, Cologne, Germany.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2015
    Article
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

P F G WolffsDepartment of Medical Microbiology, Maastricht University Medical Center, The Netherlands. p.wolffs@mumc.nl
C Vink
J Keijdener
B Habek
M Reijans
G Simons
C A Bruggeman
A J C van den Brule
PathoFinder (Netherlands) · NLMaastricht University · NLPAMM · NLUniversity Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A multiplex ligation-dependent probe amplification assay for simultaneous detection of six virus species was developed and tested on clinical cerebrospinal fluid (CSF) samples. The assay, termed MeningoFinder, showed an accordance of 97%, concordance of 96%, interlaboratory sensitivity of 90%, and interlaboratory specificity of 94% compared to PCRs.

Indexed as

Bacteriological TechniquesCentral Nervous System InfectionsCerebrospinal FluidHumansMolecular Diagnostic TechniquesNucleic Acid Amplification TechniquesReproducibility of ResultsSensitivity and SpecificityVirus DiseasesViruses

Identifiers

PMID19553572
PMCPMC2725638
OpenAlexW2108045385

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.