ArticleVirology journal2009
Klassevirus 1, a previously undescribed member of the family Picornaviridae, is globally widespread.
Article in Virology journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
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Who cites it
55 citing papers in PubMed.
- Detection and Genetic Characteristics of Cosavirus and Salivirus in the Wastewater, China.Food and environmental virology · 2025Article
- Gut virome in early life: origins and implications.Current opinion in virology · 2022Review
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- Molecular Detection of Human Salivirus in Italy Through Monitoring of Urban Sewages.Food and environmental virology · 2020Article
- Occurrence of Salivirus in Sewage and River Water Samples in Karaj, Iran.Food and environmental virology · 2019Article
- Infection and Propagation of Astrovirus VA1 in Cell Culture.Current protocols in microbiology · 2019Article
- A decade of RNA virus metagenomics is (not) enough.Virus research · 2018Review
- Molecular detection of human enteric viruses circulating among children with acute gastroenteritis in Valencia, Venezuela, before rotavirus vaccine implementation.Gut pathogens · 2018Article
- Identification of Novel Rosavirus Species That Infects Diverse Rodent Species and Causes Multisystemic Dissemination in Mouse Model.PLoS pathogens · 2016Article
- Complete Genome Sequence of a Salivirus in Respiratory Specimens from a Child with Adenovirus Infection.Genome announcements · 2016Article
- Characterization of a Salivirus (Picornaviridae) from a Diarrheal Child in Guatemala.Genome announcements · 2016Article
- Article
- Draft Genome Sequence of Laverivirus UC1, a Dicistrovirus-Like RNA Virus Featuring an Unusual Genome Organization.Genome announcements · 2015Article
- NCBI viral genomes resource.Nucleic acids research · 2015Article
- Salivirus in Children and Its Association with Childhood Acute Gastroenteritis: A Paired Case-Control Study.PloS one · 2015Article
- Picornavirus--host interactions to construct viral secretory membranes.Progress in molecular biology and translational science · 2015Review
- DNA microarray for detection of gastrointestinal viruses.Journal of clinical microbiology · 2015Article
- Epidemiology of human parechovirus, Aichi virus and salivirus in fecal samples from hospitalized children with gastroenteritis in Hong Kong.Virology journal · 2014Article
- Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names.Viruses · 2014Article
- Quantification and genetic analysis of salivirus/klassevirus in wastewater in Arizona, USA.Food and environmental virology · 2014Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundDiarrhea is the third leading infectious cause of death worldwide and is estimated to be responsible for approximately 2 million deaths a year. While many infectious causes of diarrhea have been established, approximately 40% of all diarrhea cases are of unknown etiology. In an effort to identify novel viruses that may be causal agents of diarrhea, we used high throughput mass sequencing to analyze stool samples collected from patients with acute diarrhea.
resultsSequences with limited similarity to known picornaviruses were detected in a stool sample collected in Australia from a child with acute diarrhea. Using a combination of mass sequencing, RT-PCR, 5' RACE and 3' RACE, a 6383 bp fragment of the viral genome was sequenced. Phylogenetic analysis demonstrated that this virus was highly divergent from, but most closely related to, members of the genus Kobuvirus. We have tentatively named this novel virus klassevirus 1. We also detected klassevirus 1 by RT-PCR in a diarrhea specimen collected from a patient in St. Louis, United States as well as in untreated sewage collected in Barcelona, Spain.
conclusionKlassevirus 1 is a previously undescribed picornavirus that is globally widespread and present on at least three continents. Further investigations to determine whether klassevirus 1 is a human pathogen are needed.
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