ArticleBritish journal of clinical pharmacology2009
Determinants of the drug utilization profile in the paediatric population in Italy's Lombardy Region.
Article in British journal of clinical pharmacology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Article
- A 7-Years Active Pharmacovigilance Study of Adverse Drug Reactions Causing Children Admission to a Pediatric Emergency Department in Sicily.Frontiers in pharmacology · 2020Article
- Drug Utilization Pattern of Antibiotics: The Role of Age, Sex and Municipalities in Determining Variation.Risk management and healthcare policy · 2020Article
- Gender Differences in Outpatient Pediatric Drug Utilization: A Cohort Study From Southern Italy.Frontiers in pharmacology · 2019Article
- Community Pharmacy Use by Children across Europe: A Narrative Literature Review.Pharmacy (Basel, Switzerland) · 2018Review
- Prevalence of antibiotic prescription in southern Italian outpatients: real-world data analysis of socioeconomic and sociodemographic variables at a municipality level.ClinicoEconomics and outcomes research : CEOR · 2018Article
- Drugs Delivery by Charities: A Possible Epidemiologic Indicator in Children of Undocumented Migrants.Journal of immigrant and minority health · 2017Observational
- A longitudinal comparison of drug use among 10-year-old children and 15-year-old adolescents from the German GINIplus and LISAplus birth cohorts.European journal of clinical pharmacology · 2016Article
- Antibiotic and anti-asthmatic drug prescriptions in Italy: geographic patterns and socio-economic determinants at the district level.European journal of clinical pharmacology · 2014Article
- Systemic antibiotic use among children and adolescents in Germany: a population-based study.European journal of pediatrics · 2013Article
- Drug use profile in outpatient children and adolescents in different Italian regions.BMC pediatrics · 2013Article
- Methods in pharmacoepidemiology: a review of statistical analyses and data reporting in pediatric drug utilization studies.European journal of clinical pharmacology · 2013Review
- Geographical epidemiology of antibacterials in the preschool age.International journal of health geographics · 2012Article
- The regional profile of antibiotic prescriptions in Italian outpatient children.European journal of clinical pharmacology · 2012Article
- Comparison of anti-diabetic drug prescribing in children and adolescents in seven European countries.British journal of clinical pharmacology · 2011Article
- Anti-asthma medication prescribing to children in the Lombardy Region of Italy: chronic versus new users.BMC pulmonary medicine · 2011Article
- Off-label antibiotic use in children in three European countries.European journal of clinical pharmacology · 2010Article
- Drug Utilisation Patterns in Children Admitted to a Paediatric General Medical Ward in Five Countries.Drugs - real world outcomesArticle
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6 authors.
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Abstract
aimsTo evaluate the intraregional differences in drug prescribing to children and adolescents.
methodsPrescriptions reimbursed by the National Health System, involving 1543 203 children and adolescents <18 years old and dispensed during 2005 by the retail pharmacies of 15 local health units (LHU) in the Lombardy Region, were analysed. Logistic regression analysis was performed to evaluate the association between drug prescription and age, gender, prescriber, and setting.
resultsA total of 747 790 youths (48%) received at least one drug prescription. The prescription prevalence rate was highest in children 1-5 years old (65%), decreased with increasing age to 38% in adolescents, and was slightly higher in boys than in girls. Antibiotics and anti-asthmatics were the most prescribed therapeutic classes. Amoxicillin + clavulanic acid was the most prescribed drug (18% of children; 20% of packages). Large differences were found in the drug prescription prevalence rate between the different LHUs. The rate ranged between 38.4 and 54.8%, and was not correlated to hospitalization rate in the paediatric population. Being 1-5 years old [odds ratio (OR) 4.51, 95% confidence interval (CI) 4.43, 4.58] and living in the eastern part of the region (OR 2.06, 95% CI 1.99, 2.13) were the factors associated with the highest risk of drug exposure.
conclusionsThe results resemble the profiles observed in other Italian contexts, in particular concerning the wide use of antibiotics and anti-asthmatics. However, large differences were found between LHUs, highlighting the need for more detailed investigations on therapeutic needs, drug use, and related variables in different geographic contexts.
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