Evidence map›Paper›PMID 19551389›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2009

Defenestration in children younger than 6 years old: mortality predictors in severe head trauma.

Jose Roberto Tude Melo, Federico Di Rocco, Laudenor Pereira Lemos-Júnior, Thomas Roujeau, Bertrand Thélot, Christian Sainte-Rose, Philippe Meyer, Michel Zerah

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In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Is therapeutic hypothermia beneficial for pediatric patients with traumatic brain injury? A meta-analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2013
    Pooled it
  2. Age-dependent injury mechanisms and injury patterns in pediatric window falls.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  3. Article
  4. Performance of the neutrophil-lymphocyte ratio as a predictor of severity and mortality in children and adolescents with traumatic brain injury.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
  5. A Retrospective Cohort Study of Traumatic Brain Injury in Children: A Single-Institution Experience and Determinants of Neurologic Outcome.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Jose Roberto Tude MeloDepartment of Pediatric Neurosurgery Hôpital Necker-Enfants Malades (Assistance Publique Hôpitaux de Paris-France), Université Descartes Paris 5, Paris, France. robertotude@gmail.com
Federico Di Rocco
Laudenor Pereira Lemos-Júnior
Thomas Roujeau
Bertrand Thélot
Christian Sainte-Rose
Philippe Meyer
Michel Zerah
Assistance Publique – Hôpitaux de Paris · FRHôpital Necker-Enfants Malades · FRInstitut de Veille Sanitaire · FRUniversidade Federal da Bahia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aims to describe the characteristics of severe head injuries in children less than 6 years old, victims of falls from windows, and identify the main predictive factors of mortality in this population. PATIENTS AND

methodsA cross-sectional study was designed through data derived from medical records of less than 6-year-old children victims of falls from windows presenting with a severe head injury defined by an initial Glasgow coma scale (GCS) < or =8, hospitalized at a Pediatric Trauma center level III, between January 2000 and December 2005. Statistical analysis used univariate analysis and multiple logistic regressions.

resultsWe identified 58 severe head injuries in children victims of falls from windows. The mean age was 2.8 +/- 1.4 years, with a male prevalence (64%); 48% of patients had a GCS < or =5; 62.1% had a Pediatric Trauma Score (PTS) < or =3 at hospital admission. The mortality rate was 41% (24/58) and most of them (88%; 21/24) died within 48 h. An increased death rate was noted in children admitted with hypoxemia (p = 0.001), low systolic blood pressure (p = 0.002), hypothermia (p = 0.0001), GCS < or =5 (p = 10(-5)), PTS < or =3 (p = 0.008), hyperglycemia (p = 0.023), coagulation disorders (p = 0.02), and initial intracranial pressure > or =20 mmHg (p = 0.03). Initial hypothermia, hyperglycemia, and coagulation disorders were the only independent predictive factors of mortality.

conclusionSevere head injuries resulting from falls from windows carry a high risk of mortality in less than 6-year-old children. Hypothermia, hyperglycemia, and coagulation's disorders are independent predictive factors of mortality. Early deaths could be considered as direct consequences of uncontrollable brain lesions.

Indexed as

Accidental FallsAnalysis of VarianceBlood Coagulation DisordersChildChild, PreschoolCraniocerebral TraumaCross-Sectional StudiesFemaleHumansHyperglycemiaHypothermiaInfantInfant, NewbornLogistic ModelsMalePrevalence

Identifiers

PMID19551389
OpenAlexW2075304757

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.