Evidence map›Paper›PMID 19550327›Full record

ReviewCurrent opinion in obstetrics & gynecology2009

Insulin resistance in women's health: why it matters and how to identify it.

Richard S Legro

Abstract readReview
In one paragraph

Review in Current opinion in obstetrics & gynecology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Observational
  2. The International Federation of Gynecology and Obstetrics (FIGO) initiative on pre-eclampsia: A pragmatic guide for first-trimester screening and prevention.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2019
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Richard S LegroDepartment of Obstetrics and Gynecology, Pennsylvania State University College of Medicine, M.S. Hershey Medical Center, 500 University Drive, H103, Hershey, PA 17033, USA. RSL1@psu.edu

Funding

WRITING AND THE DAILY EXPERIENCE OF ILLNESSM01RR010732 · NCRR · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI HOLOWATZ, LACY · 1995 to 2009
$29.8M
Translational Research in Polycystic Ovary SyndromeU54HD034449 · NICHD · VIRGINIA COMMONWEALTH UNIVERSITY · PI ESSAH, PAULINA A · 1997 to 2012
$15.0M
COOPERATIVE MULTICENTER REPRODUCTIVE MEDICINE NETWORKU10HD038992 · NICHD · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI LEGRO, RICHARD S. · 2000 to 2017
$5.0M
Treatment of Hyperandrogenism vs. Insulin Resistance in Infertile PCOS WomenR01HD056510 · NICHD · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI LEGRO, RICHARD S. · 2008 to 2012
$3.1M
GCRC RELOCATION AND EXPANSION PROJECTC06RR016499 · NCRR · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KIRCH, DARRELL G · 2001 to 2001
$707k
NCRR NIH HHS C06 RR016499NCRR NIH HHS M01 RR010732NCRR NIH HHS MO1RR10732NICHD NIH HHS R01 HD056510NICHD NIH HHS U10 HD038992NICHD NIH HHS U10 HD38992NICHD NIH HHS U54 HD034449NICHD NIH HHS U54 HD34449
6 · The paper itself

Abstract

purpose of reviewTo examine the significance of insulin resistance in women's health and review methods for diagnosing it. RECENT

findingsClinical phenotypes in conjunction with standard clinical biochemical assays, that is, the metabolic syndrome, remain the key method to diagnose insulin resistance in clinical practice. Candidate alleles from type 2 diabetes offer little predictive value for cardiovascular events beyond traditional risk factors. Simple environmental factors such as irregular meal frequency appear to increase the risk of the metabolic syndrome and require greater scrutiny. Pregnancy complications, particularly gestational diabetes and preeclampsia in the mother and preterm birth in the fetus are events that suggest elevated risk for future cardiovascular morbidity in those affected. SUMMARY: Clinical phenotypes of insulin resistance identify women at risk for perinatal and reproductive complications.

Indexed as

Insulin ResistanceWomen's HealthDiabetes, GestationalDiabetes Mellitus, Type 2FemaleHumansMetabolic SyndromeObesityPerinatal CarePopulation SurveillancePre-EclampsiaPregnancyReproductionRisk Factors

Identifiers

PMID19550327
PMCPMC3590839

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.