ArticleAge and ageing2009
Gait speed under varied challenges and cognitive decline in older persons: a prospective study.
Article in Age and ageing, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 5 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- The impact of walking training on cognitive function in older adults: a meta-analysis.Frontiers in psychology · 2026Pooled it
- Dual-Task Gait as a Predictive Tool for Cognitive Impairment in Older Adults: A Systematic Review.Frontiers in aging neuroscience · 2021Pooled it
- Functional parameters indicative of mild cognitive impairment: a systematic review using instrumented kinematic assessment.BMC geriatrics · 2020Pooled it
- The brain map of gait variability in aging, cognitive impairment and dementia-A systematic review.Neuroscience and biobehavioral reviews · 2017Pooled it
- The dynamic relationship between physical function and cognition in longitudinal aging cohorts.Epidemiologic reviews · 2013Pooled it
- Gait Speed and Evolution of Verbal Fluencies in Frail or Prefrail Older People with Type 2 Diabetes. A Pilot Study.The journal of nutrition, health & aging · 2021Trial
- The Impact of a Home-Based Computerized Cognitive Training Intervention on Fall Risk Measure Performance in Community Dwelling Older Adults, a Pilot Study.The journal of nutrition, health & aging · 2016Trial
- Association between balance ability and memory function in community-dwelling older adults: A cross-sectional study.Medicine · 2026Article
- Real-world walking patterns are associated with regional brain atrophy and white matter lesions in middle-aged and older people: a Watch Walk-UK Biobank study.GeroScience · 2026Article
- Gait speed and domain-specific cognitive performance in a diverse cohort of the oldest-old: the LifeAfter90 Study.GeroScience · 2026Article
- Single-task, dual-task, and community gait speeds of older adults in Singapore: their associations with frailty, cognition, and age-friendly cities.Innovation in aging · 2026Article
- Nutritional intervention targeting muscle-brain axis in dementia continuum: from mechanisms to practice.Frontiers in nutrition · 2026Review
- Relationship of Alzheimer's Disease and Related Dementias Plasma Biomarkers With Mobility in Cognitively Unimpaired Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Biological and Physical Performance Markers for Early Detection of Cognitive Impairment in Older Adults.Journal of clinical medicine · 2024Review
- Association Between Contrast Sensitivity and Physical Function in Cognitively Healthy Older Adults: The Brain Networks and Mobility Function Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Lower Myelin Content Is Associated With Lower Gait Speed in Cognitively Unimpaired Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Gradient and Acceleration of Decline in Physical and Cognitive Functions in Older Adults: A Disparity Analysis.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- Association among cognitive function, physical fitness, and health status in older women.Journal of exercise rehabilitation · 2022Article
- Article
- Random walk: Random number generation during backward and forward walking- the role of aging.Frontiers in aging neuroscience · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveto examine whether usual gait speed, fast gait speed or speed while walking with a cognitive or neuromuscular challenge predicts evolving cognitive decline over 3 years.
designprospective study.
settingpopulation-based sample of community-dwelling older persons.
participants660 older participants (age > or = 65 years). MEASUREMENTS: usual gait speed, fastest gait speed, gait speed during 'walking-while-talking', depression, comorbidities, education, smoking and demographics were assessed at baseline. Cognition was evaluated at baseline and follow-up. A decline in MMSE score by > or = 3 points was considered as significant cognitive decline (SCD).
resultsadjusting for confounders, only fast speed was associated with cognitive performance at 3-year follow-up. One hundred thirty-five participants had SCD over 3 years. Participants in the lowest quartile of usual speed or walking-while-talking speed were more likely to develop SCD. Conversely, participants in the third and fourth quartiles of fast speed were more likely to develop SCD. J-test showed that the model including fast speed quartiles as a regressor was significantly more predictive of SCD than the models with usual speed or walking-while-talking speed quartiles.
conclusionmeasuring fast gait speed in older persons may assist in identifying those at high risk of cognitive decline.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.