Evidence map›Paper›PMID 19549523›Full record

ReviewGastroenterology2009

Coinfection with HIV-1 and HCV--a one-two punch.

Arthur Y Kim, Raymond T Chung

Abstract readReview
In one paragraph

Review in Gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed.

  1. Article
  2. Article
  3. Expression ofMedicina (Kaunas, Lithuania) · 2023
    Article
  4. Human Immunodeficiency Virus Is Associated With Elevated FibroScan-Aspartate Aminotransferase (FAST) Score.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. The involvement of microRNAs in HCV and HIV infection.Therapeutic advances in vaccines and immunotherapy · 2022
    Review
  11. IdentifyingJournal of immunology research · 2022
    Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Plasma Inflammatory Biomarkers Associated with Advanced Liver Fibrosis in HIV-HCV-Coinfected Individuals.International journal of environmental research and public health · 2020
    Article
  18. Review
  19. Article
  20. Article

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Arthur Y KimDivision of Infectious Diseases and the Ragon Institute of MGH, MIT, and Harvard, Boston, Massachusetts, USA. akim1@partners.org
Raymond T Chung

Funding

The role of NK cells during acute HCV infection and antiviral therapyU19AI066345 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI RODRIGUES, LIA LEWIS-XIMENEZ DE SOUZA · 2005 to 2014
$8.5M
HIV-Hepatitis C Virus Interactions and PathogenesisR01AI069939 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CHUNG, RAYMOND T · 2006 to 2010
$1.9M
Patient-Oriented Research on Hepatitis in Special PopulationsK24DK078772 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI CHUNG, RAYMOND T · 2007 to 2016
$1.6M
Cell-mediated Immunity to HCV in HIV+ PersonsK23AI054379 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI KIM, ARTHUR Y · 2003 to 2007
$649k
NIAID NIH HHS K23 AI054379NIAID NIH HHS R01 AI069939NIAID NIH HHS U19 AI066345NIDDK NIH HHS K24 DK078772
6 · The paper itself

Abstract

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, cirrhosis, and death; it is estimated that 180 million persons are infected with HCV worldwide. The consequences of HCV are worse in those who are coinfected with human immunodeficiency virus 1 (HIV-1), which is unfortunately a common scenario because of shared risk factors of the viruses. More studies into effects of HCV/HIV-1 coinfection are needed, but efforts have been hampered by limitations in our understanding of the combined pathogenesis of the 2 viruses. Gaining insight into the mechanisms that underlie the immunopathogenesis of these persistent viral infections could lead to new therapeutic strategies for patients with HCV/HIV-1 coinfection.

Indexed as

HIV-1AnimalsDisease ProgressionHepacivirusHepatitis C, ChronicHIV InfectionsHomosexuality, MaleHumansImmunity, ActiveImmunity, InnateLiver DiseasesMaleSubstance Abuse, IntravenousVirus Replication

Identifiers

PMID19549523
PMCPMC3146750

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.