Evidence map›Paper›PMID 19549056›Full record

ArticleAddiction (Abingdon, England)2009

Adolescent smoking and depression: evidence for self-medication and peer smoking mediation.

Janet Audrain-McGovern, Daniel Rodriguez, Jon D Kassel

Abstract read
In one paragraph

Article in Addiction (Abingdon, England), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. The Association of Cigarette Smoking With Depression and Anxiety: A Systematic Review.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017
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  11. A Cross Sectional Study on the Risk Perceptions and Barriers towards Smoking Cessation in a Rural Setting in Goa.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2025
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  15. Mendelian Randomization Analysis of the Causal Effect of Cigarette Smoking on Hospital Costs.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
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38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Janet Audrain-McGovernDepartment of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA. audrain@mail.med.upenn.edu
Daniel Rodriguez
Jon D Kassel

Funding

Longitudinal Patterns and Predictors of Smoking BehaviorR01CA109250 · NCI · UNIVERSITY OF PENNSYLVANIA · PI AUDRAIN-MCGOVERN, JANET E · 2004 to 2008
$1.2M
NCI NIH HHS R01 CA109250NCI NIH HHS R01CA109250PHS HHS P50 84718
6 · The paper itself

Abstract

aimsThe nature of the relationship between adolescent smoking and depression is unclear and the mechanisms that account for the comorbidity have received little investigation. The present study sought to clarify the temporal precedence for smoking and depression and to determine whether these variables are linked indirectly through peer smoking.

participantsThe sample was composed of 1093 adolescents participating in a longitudinal study of the behavioral predictors of smoking adoption. DESIGN AND MEASUREMENTS: In this prospective cohort study, smoking, depression, peer smoking and other covariates were measured annually from mid-adolescence (9th grade; age 14) to late adolescence (12th grade, age 18).

findingsParallel processes latent growth curve models supported a bidirectional relationship between adolescent smoking and depression, where higher depression symptoms in mid-adolescence (age 14) predicted adolescent smoking progression from mid- to late adolescence (ages 14-18). A significant indirect effect indicated that higher depression symptoms across time predicted an increase in the number of smoking peers, which in turn predicted smoking progression from mid-adolescence to late adolescence. In addition, smoking progression predicted a deceleration of depression symptoms from mid- to late adolescence. A significant indirect effect indicated that greater smoking at baseline predicted a deceleration in the number of smoking peers across time, which predicted a deceleration in depression symptoms from mid-adolescence to late adolescence.

conclusionsThe current study provides the first evidence of bidirectional self-medication processes in the relationship between adolescent smoking and depression and highlights peer smoking as one explanation for the comorbidity.

Indexed as

Health Knowledge, Attitudes, PracticeModels, StatisticalPeer GroupAdolescentComorbidityData Interpretation, StatisticalDepressionFemaleHumansMaleProspective StudiesSmokingSocial Facilitation

Identifiers

PMID19549056
PMCPMC2891382

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.