Evidence map›Paper›PMID 19548666›Full record

ArticleAnalytical chemistry2009

Wireless, remote-query, and high sensitivity Escherichia coli O157:H7 biosensor based on the recognition action of concanavalin A.

Qingzhu Lu, Hailan Lin, Shutian Ge, Shenglian Luo, Qingyun Cai, Craig A Grimes

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 59 citations in OpenAlex.

  1. Expediting Glycospace Exploration: Therapeutic Glycans via Automated Synthesis.Angewandte Chemie (International ed. in English) · 2025
    Review
  2. Article
  3. Recent Progress in Lectin-Based Biosensors.Materials (Basel, Switzerland) · 2015
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Qingzhu LuState Key Laboratory of Chemo/Biosensing and Chemometrics, Department of Chemistry, Hunan University, Changsha 410082, P.R. China.
Hailan Lin
Shutian Ge
Shenglian Luo
Qingyun Cai
Craig A Grimes
Hunan University · CNPennsylvania State University · US

Funding

Endotoxin Quantification in Aqueous MediaR21EB006397 · NIBIB · PENNSYLVANIA STATE UNIVERSITY, THE · PI GRIMES, CRAIG A · 2006 to 2007
$392k
NIBIB NIH HHS 5 R21 EB006397-02NIBIB NIH HHS R21 EB006397
6 · The paper itself

Abstract

Escherichia coli O157:H7 is detected using a remote-query (wireless, passive) magnetoelastic sensor platform to which a 1 microm thick layer of Bayhydrol 110 and then a layer of functionalized mannose is applied. The multivalent binding of lectin concanavalin A (Con A) to the E. coli surface O-antigen and mannose favors the strong adhesion of E. coli to the mannose-modified magnetoelastic sensor; E. coli is rigidly and strongly attached on the mannose-modified sensor through Con A, which works as a bridge to bind E. coli to the mannose-modified sensor surface. As E. coli is bound to the sensor, its resonance frequency shifts, enabling quantification of E. coli concentration with a limit of detection of 60 cells/mL and a linear logarithmic response range of 6.0 x 10(1) to 6.1 x 10(9) cells/mL. The analysis can be directly conducted without incubation and completed in 3 h or less.

Indexed as

AdsorptionAsepsisBiosensing TechniquesCalciumConcanavalin AEscherichia coli O157MagneticsManganeseMannoseO AntigensSubstrate SpecificityTime FactorsCalciumConcanavalin AManganeseMannoseO Antigens

Identifiers

PMID19548666
PMCPMC2735831
OpenAlexW2019072196

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.