ReviewClinical reviews in allergy & immunology2010
Antifibrosis: to reverse the irreversible.
Review in Clinical reviews in allergy & immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Available and novel plant-based carbon dots derived from Vaccaria Semen carbonisata alleviates liver fibrosis.Frontiers in molecular biosciences · 2023Article
- Article
- Shugan Huoxue Huayu Fang attenuates carbon tetrachloride-induced hepatic fibrosis in rats by inhibiting transforming growth factor-β1/Smad signaling.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2022Article
- Effects of New NSAID-CAI Hybrid Compounds in Inflammation and Lung Fibrosis.Biomolecules · 2020Article
- Effects of PARP-1 Deficiency and Histamine HFrontiers in pharmacology · 2019Article
- Amifostine Analog, DRDE-30, Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice.Frontiers in pharmacology · 2018Article
- Sequential Release of Multiple Drugs from Flexible Drug Delivery Films.International journal of polymeric materials · 2017Article
- Green tea polyphenols and their potential role in health and disease.Inflammopharmacology · 2015Review
- Green tea extract therapy diminishes hepatic fibrosis mediated by dual exposure to carbon tetrachloride and ethanol: A histopathological study.Experimental and therapeutic medicine · 2015Article
- Role and New Insights of Pirfenidone in Fibrotic Diseases.International journal of medical sciences · 2015Review
- Differentiating Glomerular Inflammation from Fibrosis in a Bone Marrow Chimera for Rat Anti-Glomerular Basement Membrane Glomerulonephritis.American journal of nephrology · 2015Article
- Curative propensity of green tea extract towards hepatic fibrosis induced by CCl(4): A histopathological study.Experimental and therapeutic medicine · 2012Article
- The future of autoimmunity.Clinical reviews in allergy & immunology · 2012Article
- Themes in fibrosis and gastrointestinal inflammation.American journal of physiology. Gastrointestinal and liver physiology · 2011Article
- Microtopographical cues in 3D attenuate fibrotic phenotype and extracellular matrix deposition: implications for tissue regeneration.Tissue engineering. Part A · 2010Article
- Scarless wound healing.The journal of the American College of Certified Wound Specialists · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fibrosis is a pathological process that includes scar formation and overproduction of extracellular matrix by the connective tissue as a response to tissue damage. The fibrotic process involves multiple organs and results in progressive life-threatening diseases. Today, we know more about the molecular mechanism that leads to fibrosis involving different type of cells, cytokines, chemokines, and tissue enzymes. Fibrosis was considered an irreversible process, at least clinically, and is still usually treated by anti-inflammatory and immunosuppressive agents. No proven antifibrotic therapy has shown efficacy in ameliorating the clinical course of fibrotic diseases, but our current understanding led to the development of different drugs with promising results, like: mycophenolate mofetil, interferon, relaxin, and intravenous immunoglobulin. This review will provide a glance to this heavily investigated subject.
Indexed as
Identifiers
19548121What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.