ArticleCurrent genetics2009
The MAPKK kinase ChSte11 regulates sexual/asexual development, melanization, pathogenicity, and adaptation to oxidative stress in Cochliobolus heterostrophus.
Article in Current genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 57 citations in OpenAlex.
- ChnagG Plays the Role of 5-Salicylate Hydroxylase in the Gentisic Acid Pathway of Salicylic Acid Metabolism in Cochliobolus heterostrophus.Molecular plant pathology · 2025Article
- Homeobox transcription factor BmHox7 is required for sexual reproduction, but not for appressorial development and pathogenicity inMycoscience · 2025Article
- Dual regulation of appressorium development in the maize pathogenMycoscience · 2025Article
- Hydrophobins inFrontiers in fungal biology · 2025Article
- Protein Kinase PoxMKK1 Regulates Plant-Polysaccharide-Degrading Enzyme Biosynthesis, Mycelial Growth and Conidiation inJournal of fungi (Basel, Switzerland) · 2023Article
- Cell Wall Integrity and Its Industrial Applications in Filamentous Fungi.Journal of fungi (Basel, Switzerland) · 2022Review
- Meiotic Silencing in DothideomycetousFrontiers in fungal biology · 2022Article
- An exocyst component, Sec5, is essential for ascospore formation inMycoscience · 2021Article
- Cla4 PAK-like kinase is required for pathogenesis, asexual/sexual development and polarized growth in Bipolaris maydis.Current genetics · 2019Article
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- The Interactomic Analysis Reveals Pathogenic Protein Networks inFrontiers in genetics · 2018Article
- ChSte7 Is Required for Vegetative Growth and Various Plant Infection Processes in Colletotrichum higginsianum.BioMed research international · 2016Article
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- Isolation and Identification of Pathogenicity Mutant of Curvularia lunata via Restriction Enzyme-Mediated Integration.Indian journal of microbiology · 2013Article
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- Mitogen-activated protein kinase signaling in plant-interacting fungi: distinct messages from conserved messengers.The Plant cell · 2012Review
- Characterization of CpSte11, a MAPKKK gene of Cryphonectria parasitica, and initial evidence of its involvement in the pheromone response pathway.Molecular plant pathology · 2012Article
- MAPK machinery in plants: recognition and response to different stresses through multiple signal transduction pathways.Plant signaling & behavior · 2010Review
- A copper-transporting ATPase BcCCC2 is necessary for pathogenicity of Botrytis cinerea.Molecular genetics and genomics : MGG · 2010Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
All fungi use multiple mitogen-activated protein kinase (MAPK) cascades to respond to external signals to regulate specialized responses. In this study, we cloned and characterized a putative MAPKKK gene ChSte11, orthologous to yeast STE11, of Cochliobolus heterostrophus. DeltaChste11 strains showed defects in conidiation, sexual development, melanization and the formation of appressoria. These mutants were significantly less virulent on corn plants than the wild type. Similar phenotypes were observed in mutants of Chk1-MAPK, a putative downstream protein kinase of ChSte11. These results suggested that ChSte11 regulates various morphological changes and pathogenicity via Chk1 MAPK. Both DeltaChste11 and Deltachk1 strains showed severe sensitivity to oxidative stress, hydrogen peroxide, and heavy metals, cupric or ferric cations. DeltaBmhog1 strains, mutants of the HOG1-type MAPK, did not show sensitivity to these forms of stress. Our results strongly suggested that the Ste11-type MAPKKK regulates not only various morphological changes and pathogenicity, but also adaptations to stress via Chk1-type MAPK in filamentous fungi.
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