ArticleIntensive care medicine2009
Relationships among haemoglobin level, packed red cell transfusion and clinical outcomes in patients after cardiac surgery.
Article in Intensive care medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Safety and effects of two red blood cell transfusion strategies in pediatric cardiac surgery patients: a randomized controlled trial.Intensive care medicine · 2013Trial
- Intra-operative intravenous fluid restriction reduces perioperative red blood cell transfusion in elective cardiac surgery, especially in transfusion-prone patients: a prospective, randomized controlled trial.Journal of cardiothoracic surgery · 2010Trial
- Predictors and prognostic value for in-hospital outcomes associated with postoperative anemia in cardiac surgery: a retrospective cohort study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2026Article
- Article
- Postoperative anemia in cardiac surgery patients: a narrative review.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024Review
- Current Practices and Guidelines for Perioperative Blood Management in Post-Bariatric Body Contouring Surgery: A Comprehensive Review of Literature.Aesthetic plastic surgery · 2023Review
- Decrease in Haemoglobin in Association with Aneurysm Volume Loss after Endovascular Repair of Abdominal Aortic Aneurysm.Reviews in cardiovascular medicine · 2023Article
- Study of the accuracy of a radial arterial pressure waveform cardiac output measurement device after cardiac surgery.Journal of cardiothoracic surgery · 2023Observational
- The influence of postoperative albumin levels on the outcome of cardiac surgery.Journal of cardiothoracic surgery · 2020Observational
- Blood transfusions increase the risk of venous thromboembolism following ventral hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2019Article
- The Effect of Preoperative Anemia on the Outcome After Coronary Surgery.World journal of surgery · 2017Article
- Influence of cirrhosis in cardiac surgery outcomes.World journal of hepatology · 2015Review
- Influence of acute kidney injury on short- and long-term outcomes in patients undergoing cardiac surgery: risk factors and prognostic value of a modified RIFLE classification.Critical care (London, England) · 2013Article
- What's new in transfusion policies?Intensive care medicine · 2013Article
- Red blood cell transfusion affects microdialysis-assessed interstitial lactate/pyruvate ratio in critically ill patients with late sepsis.Intensive care medicine · 2012Article
- Postoperative red blood cell transfusion and morbid outcome in uncomplicated cardiac surgery patients.Intensive care medicine · 2011Article
- Red blood cell transfusion and increased length of storage are not associated with deep vein thrombosis in medical and surgical critically ill patients: a prospective observational cohort study.Critical care (London, England) · 2011Article
- Year in review in Intensive Care Medicine 2009. Part III: mechanical ventilation, acute lung injury and respiratory distress syndrome, pediatrics, ethics, and miscellanea.Intensive care medicine · 2010Review
- Association between length of storage of red blood cell units and outcome of critically ill children: a prospective observational study.Critical care (London, England) · 2010Article
- Getting it right: optimizing transfusion management during the procedure.The journal of extra-corporeal technology · 2009Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo identify associations among haemoglobin (Hb) concentrations, blood transfusions, and clinical outcomes in patients after cardiac surgery, especially in those who undergo valve replacement or bypass surgery.
designProspective observational trial.
settingSurgical intensive care unit in a tertiary-level university hospital. PATIENTS: 1216 Consecutive patients. MEASUREMENTS: Haemoglobin at admission and 6, 12, 24, and 48 h later, and then, every 24 h while patients remained in the intensive care unit (ICU); number of transfusions and clinical events.
resultsPatients were divided into quartiles according to minimal haemoglobin, the first and second of which (Hb <8.10 and <8.91 g/dL, respectively) differed significantly (P < 0.001) from the other two quartiles in terms of more organ failure, longer ICU stay, and higher mortality. We found associations between being transfused >or=4 packed red cells (PRCs) and a worse clinical outcome and higher mortality. The associated mortality rate was higher for patients who underwent bypass surgery when they had Hb <or=8.9 g/dL and for those who underwent valve replacement when they had Hb >8.9 g/dL and were transfused >or=4 PRCs.
conclusionsLow haemoglobin concentrations and transfusions in patients undergoing cardiac surgery are associated with increased morbidity and mortality. Also, anemia and transfusions are associated with poor outcome. Therefore, intra- and postoperative bleeding seem to be a risk factor in patients undergoing cardiac surgery.
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