Evidence map›Paper›PMID 19545438›Full record

ArticleJournal of experimental & clinical cancer research : CR2009

Non-Hodgkin lymphoma response evaluation with MRI texture classification.

Lara C V Harrison, Tiina Luukkaala, Hannu Pertovaara, Tuomas O Saarinen, Tomi T Heinonen, Ritva Järvenpää, Seppo Soimakallio, Pirkko-Liisa I Kellokumpu-Lehtinen, Hannu J Eskola, Prasun Dastidar

Abstract readEvaluation Study
In one paragraph

Article in Journal of experimental & clinical cancer research : CR, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Quantifying tumour heterogeneity in 18F-FDG PET/CT imaging by texture analysis.European journal of nuclear medicine and molecular imaging · 2013
    Review
  12. Article
  13. MRI texture analysis in multiple sclerosis.International journal of biomedical imaging · 2012
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lara C V HarrisonTampere University Medical School, Tampere, Finland. lara.harrison@tut.fi
Tiina Luukkaala
Hannu Pertovaara
Tuomas O Saarinen
Tomi T Heinonen
Ritva Järvenpää
Seppo Soimakallio
Pirkko-Liisa I Kellokumpu-Lehtinen
Hannu J Eskola
Prasun Dastidar

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo show magnetic resonance imaging (MRI) texture appearance change in non-Hodgkin lymphoma (NHL) during treatment with response controlled by quantitative volume analysis.

methodsA total of 19 patients having NHL with an evaluable lymphoma lesion were scanned at three imaging timepoints with 1.5T device during clinical treatment evaluation. Texture characteristics of images were analyzed and classified with MaZda application and statistical tests.

resultsNHL tissue MRI texture imaged before treatment and under chemotherapy was classified within several subgroups, showing best discrimination with 96% correct classification in non-linear discriminant analysis of T2-weighted images.Texture parameters of MRI data were successfully tested with statistical tests to assess the impact of the separability of the parameters in evaluating chemotherapy response in lymphoma tissue.

conclusionTexture characteristics of MRI data were classified successfully; this proved texture analysis to be potential quantitative means of representing lymphoma tissue changes during chemotherapy response monitoring.

Indexed as

Magnetic Resonance ImagingAdultAgedAntineoplastic AgentsFemaleHumansImage Interpretation, Computer-AssistedLymphoma, Non-HodgkinMaleMiddle AgedPrognosisAntineoplastic Agents

Identifiers

PMID19545438
PMCPMC2711966

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.