SynthesisBMC genomics2009
Improved resolution in the position of drought-related QTLs in a single mapping population of rice by meta-analysis.
Synthesis in BMC genomics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Understanding complex genetic architecture of rice grain weight through QTL-meta analysis and candidate gene identification.Scientific reports · 2022Pooled it
- Pooled it
- Meta-Analyses of QTLs Associated with Protein and Oil Contents and Compositions in Soybean [Glycine max (L.) Merr.] Seed.International journal of molecular sciences · 2017Pooled it
- Meta-analysis of major QTL for abiotic stress tolerance in barley and implications for barley breeding.Planta · 2017Pooled it
- Quantitative Trait Locus (QTL) meta-analysis and comparative genomics for candidate gene prediction in perennial ryegrass (Lolium perenne L.).BMC genetics · 2012Pooled it
- Meta-analysis of grain yield QTL identified during agricultural drought in grasses showed consensus.BMC genomics · 2011Pooled it
- Meta-analysis of cotton fiber quality QTLs across diverse environments in a Gossypium hirsutum x G. barbadense RIL population.BMC plant biology · 2010Pooled it
- OsPIP2;1 impacts root hydraulic conductance and is a candidate gene for a drought avoidance QTL on rice chromosome 7.Plant biology (Stuttgart, Germany) · 2026Article
- CRISPR/Cas-mediated genome editing: playing a versatile role in mitigating the challenges of sustainable rice improvement.3 Biotech · 2025Review
- Uncovering the Genomic Regions Associated with Yield Maintenance in Rice Under Drought Stress Using an Integrated Meta-Analysis Approach.Rice (New York, N.Y.) · 2024Article
- Meta-QTL mapping for wheat thousand kernel weight.Frontiers in plant science · 2024Article
- Traces of Introgression from cAus into Tropical Japonica Observed in African Upland Rice Varieties.Rice (New York, N.Y.) · 2023Article
- Root system architecture in rice: impacts of genes, phytohormones and root microbiota.3 Biotech · 2022Review
- Meta-analysis of QTLs and candidate genes associated with seed germination in rice (Physiology and molecular biology of plants : an international journal of functional plant biology · 2022Article
- Meta-QTL analysis and candidate genes identification for various abiotic stresses in maize (Molecular breeding : new strategies in plant improvement · 2022Article
- Large-scale integration of meta-QTL and genome-wide association study discovers the genomic regions and candidate genes for yield and yield-related traits in bread wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Meta-Analysis of Quantitative Traits Loci (QTL) Identified in Drought Response in Rice (Plants (Basel, Switzerland) · 2021Article
- Characterization of black spot resistance in diploid roses with QTL detection, meta-analysis and candidate-gene identification.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Article
- Meta-QTL analysis and identification of candidate genes for drought tolerance in bread wheat (Physiology and molecular biology of plants : an international journal of functional plant biology · 2020Article
- Identification and Validation of Aerobic Adaptation QTLs in Upland Rice.Life (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundMeta-analysis of QTLs combines the results of several QTL detection studies and provides narrow confidence intervals for meta-QTLs, permitting easier positional candidate gene identification. It is usually applied to multiple mapping populations, but can be applied to one. Here, a meta-analysis of drought related QTLs in the Bala x Azucena mapping population compiles data from 13 experiments and 25 independent screens providing 1,650 individual QTLs separated into 5 trait categories; drought avoidance, plant height, plant biomass, leaf morphology and root traits. A heat map of the overlapping 1 LOD confidence intervals provides an overview of the distribution of QTLs. The programme BioMercator is then used to conduct a formal meta-analysis at example QTL clusters to illustrate the value of meta-analysis of QTLs in this population.
resultsThe heat map graphically illustrates the genetic complexity of drought related traits in rice. QTLs can be linked to their physical position on the rice genome using Additional file 1 provided. Formal meta-analysis on chromosome 1, where clusters of QTLs for all trait categories appear close, established that the sd1 semi-dwarfing gene coincided with a plant height meta-QTL, that the drought avoidance meta-QTL was not likely to be associated with this gene, and that this meta-QTL was not pleiotropic with close meta-QTLs for leaf morphology and root traits. On chromosome 5, evidence suggests that a drought avoidance meta-QTL was pleiotropic with leaf morphology and plant biomass meta-QTLs, but not with meta-QTLs for root traits and plant height 10 cM lower down. A region of dense root QTL activity graphically visible on chromosome 9 was dissected into three meta-QTLs within a space of 35 cM. The confidence intervals for meta-QTLs obtained ranged from 5.1 to 14.5 cM with an average of 9.4 cM, which is approximately 180 genes in rice.
conclusionThe meta-analysis is valuable in providing improved ability to dissect the complex genetic structure of traits, and distinguish between pleiotropy and close linkage. It also provides relatively small target regions for the identification of positional candidate genes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.