Trial reportBMC medical research methodology2009
Identifying strategies to maximise recruitment and retention of practices and patients in a multicentre randomised controlled trial of an intervention to optimise secondary prevention for coronary heart disease in primary care.
Trial report in BMC medical research methodology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03511482 (An Open Feasibility Study to Investigate the Impact of A Digitally Delivered Asthma Service for Patients in Primary Care), which is not on this map. Cited by 32 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An Open Feasibility Study to Investigate the Impact of A Digitally Delivered Asthma Service for Patients in Primary Care (IDEAL-001: Integrated Digitally EnhAnced Care for Long-term Conditions-001
Who cites it
32 citing papers in PubMed, 5 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- What works to recruit general practices to trials? A rapid review.HRB open research · 2023Pooled it
- Does advance contact with research participants increase response to questionnaires: an updated systematic review and meta-analysis.BMC medical research methodology · 2021Pooled it
- Withdrawal reasons of randomized controlled trials on type 2 diabetes: a systematic review.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2021Pooled it
- The effectiveness of recruitment strategies on general practitioner's survey response rates - a systematic review.BMC medical research methodology · 2014Pooled it
- Strategies to improve retention in randomised trials.The Cochrane database of systematic reviews · 2013Pooled it
- Baseline characteristics and comparability of older multimorbid patients with polypharmacy and general practitioners participating in a randomized controlled primary care trial.BMC family practice · 2021Trial
- Recruiting general practitioners and patients with dementia into a cluster randomised controlled trial: strategies, barriers and facilitators.BMC medical research methodology · 2021Trial
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- GPs' role security and therapeutic commitment in managing alcohol problems: a randomised controlled trial of a tailored improvement programme.BMC family practice · 2014Trial
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- Assessment of data quality in an international multi-centre randomised trial of coronary artery surgery.Trials · 2011Trial
- Maximizing retention with high risk participants in a clinical trial.American journal of health promotion : AJHPTrial
- Primary care involvement in clinical research - prerequisites, motivators, and barriers: results from a study series.Archives of public health = Archives belges de sante publique · 2024Article
- New Home, New You: A retrospective mixed-methods evaluation of a health-related behavioural intervention programme supporting social housing tenants.Health expectations : an international journal of public participation in health care and health policy · 2023Article
- Recruitment and retention of primary care practices in the Southeastern Collaboration to Improve Blood Pressure Control.Contemporary clinical trials communications · 2023Article
- Utility of HIV support groups in advancing implementation research in resource-limited settings: experiences from an urban-setting HIV support group in Zimbabwe.AIDS research and therapy · 2022Article
- Recruitment strategies for a pragmatic cluster randomized oral health trial in pediatric primary care settings.Contemporary clinical trials communications · 2021Article
- Acceptability and feasibility of conducting a pilot trial in Irish primary care: lessons from the IDEAs study.HRB open research · 2021Article
- Shared decision-making (SHARE-D) for healthy behaviour change: a feasibility study in general practice.BJGP open · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundRecruitment and retention of patients and healthcare providers in randomised controlled trials (RCTs) is important in order to determine the effectiveness of interventions. However, failure to achieve recruitment targets is common and reasons why a particular recruitment strategy works for one study and not another remain unclear. We sought to describe a strategy used in a multicentre RCT in primary care, to report researchers' and participants' experiences of its implementation and to inform future strategies to maximise recruitment and retention.
methodsIn total 48 general practices and 903 patients were recruited from three different areas of Ireland to a RCT of an intervention designed to optimise secondary prevention of coronary heart disease. The recruitment process involved telephoning practices, posting information, visiting practices, identifying potential participants, posting invitations and obtaining consent. Retention involved patients attending reviews and responding to questionnaires and practices facilitating data collection.
resultsWe achieved high retention rates for practices (100%) and for patients (85%) over an 18-month intervention period. Pilot work, knowledge of the setting, awareness of change in staff and organisation amongst participant sites, rapid responses to queries and acknowledgement of practitioners' contributions were identified as being important. Minor variations in protocol and research support helped to meet varied, complex and changing individual needs of practitioners and patients and encouraged retention in the trial. A collaborative relationship between researcher and practice staff which required time to develop was perceived as vital for both recruitment and retention.
conclusionRecruiting and retaining the numbers of practices and patients estimated as required to provide findings with adequate power contributes to increased confidence in the validity and generalisability of RCT results. A continuous dynamic process of monitoring progress within trials and tailoring strategies to particular circumstances, whilst not compromising trial protocols, should allow maximal recruitment and retention.
trial registrationISRCTN24081411.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.