ArticleThe Journal of infectious diseases2009
Importance of the epa locus of Enterococcus faecalis OG1RF in a mouse model of ascending urinary tract infection.
Article in The Journal of infectious diseases, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 35 citations in OpenAlex.
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- An Overview of the Factors Involved in Biofilm Production by theInternational journal of molecular sciences · 2023Review
- Phage Cocktails Constrain the Growth ofmSystems · 2022Article
- Cell wall polysaccharides of Gram positive ovococcoid bacteria and their role as bacteriophage receptors.Computational and structural biotechnology journal · 2021Review
- Role ofJournal of bacteriology · 2019Article
- Pathogenicity of Enterococci.Microbiology spectrum · 2019Review
- Decoration of the enterococcal polysaccharide antigen EPA is essential for virulence, cell surface charge and interaction with effectors of the innate immune system.PLoS pathogens · 2019Article
- Loss of a Major Enterococcal Polysaccharide Antigen (Epa) byAntimicrobial agents and chemotherapy · 2019Article
- Review
- Restructuring ofNPJ biofilms and microbiomes · 2017Article
- Clinical characteristics and risk factors of enterococcal infections in Nagasaki, Japan: a retrospective study.BMC infectious diseases · 2015Article
- Surface-Associated Lipoproteins Link Enterococcus faecalis Virulence to Colitogenic Activity in IL-10-Deficient Mice Independent of Their Expression Levels.PLoS pathogens · 2015Article
- Role of glycolipids in the pathogenesis of Enterococcus faecalis urinary tract infection.PloS one · 2014Article
- Transcriptomic and functional analysis of NaCl-induced stress in Enterococcus faecalis.PloS one · 2014Article
- Frequency of ace, epa and elrA Genes in Clinical and Environmental Strains of Enterococcus faecalis.Indian journal of microbiology · 2012Article
- Efficacy of ceftobiprole Medocaril against Enterococcus faecalis in a murine urinary tract infection model.Antimicrobial agents and chemotherapy · 2012Article
- The rise of the Enterococcus: beyond vancomycin resistance.Nature reviews. Microbiology · 2012Review
- Relative contributions of Ebp Pili and the collagen adhesin ace to host extracellular matrix protein adherence and experimental urinary tract infection by Enterococcus faecalis OG1RF.Infection and immunity · 2011Article
- Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Previously, TX5179, a disruption mutant of the enterococcal polysaccharide antigen (epa) gene cluster of Enterococcus faecalis strain OG1RF was shown to be attenuated in translocation, biofilm, mouse peritonitis and was more susceptible to polymorphonuclear leukocyte phagocytic killing. Here, wild-type E. faecalis OG1RF and TX5179 strains were tested in a mixed-infection (inoculum, approximately 1:1) mouse urinary tract infection model. Wild-type OG1RF outnumbered TX5179 in the kidneys (P < .001) and bladder (P < .001). In conclusion, the epa locus of E. faecalis OG1RF contributes to murine urinary tract infection and is the first such enterococcal polysaccharide locus shown to be important in this site.
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Registered trials
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