Evidence map›Paper›PMID 19543908›Full record

Trial reportEuropean journal of applied physiology2009

Different response to eccentric and concentric training in older men and women.

Matthias Mueller, Fabio Andreas Breil, Michael Vogt, Roger Steiner, Kurt Lippuner, Albrecht Popp, Stephan Klossner, Hans Hoppeler, Christoph Däpp

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04099316 (Effects of Eccentric-based Training on Muscle Strength and Physical Function in Older Adults), which is not on this map. Cited by 48 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 4 pooled it
11.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04099316 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Effects of Eccentric-based Training on Muscle Strength and Physical Function in Older Adults

TypeinterventionalSponsorSeoul National University Bundang HospitalRan2017 to 2019Enrolled27ConditionsSarcopeniaArmsEccentric exercise, Conventional resistance exercise
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 4 syntheses or guidelines pooled it, 111 citations in OpenAlex.

  1. Guideline
  2. Chronic Adaptations to Eccentric Cycling Training: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2023
    Pooled it
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  12. Review
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  20. Moving forward with backward pedaling: a review on eccentric cycling.European journal of applied physiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Matthias MuellerInstitute of Anatomy, University of Bern, Baltzerstrasse 2, 3000, Bern 9, Switzerland. matthias.mueller@ana.unibe.ch
Fabio Andreas Breil
Michael Vogt
Roger Steiner
Kurt Lippuner
Albrecht Popp
Stephan Klossner
Hans Hoppeler
Christoph Däpp
University of Bern · CHUniversity Hospital of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcopenia is the age-related loss of muscle mass and strength and has been associated with an increased risk of falling and the development of metabolic diseases. Various training protocols, nutritional and hormonal interventions have been proposed to prevent sarcopenia. This study explores the potential of continuous eccentric exercise to retard age-related loss of muscle mass and function. Elderly men and women (80.6 +/- 3.5 years) were randomized to one of three training interventions demanding a training effort of two sessions weekly for 12 weeks: cognitive training (CT; n = 16), conventional resistance training (RET; n = 23) and eccentric ergometer training (EET; n = 23). Subjects were tested for functional parameters and body composition. Biopsies were collected from M. vastus lateralis before and after the intervention for the assessment of fiber size and composition. Maximal isometric leg extension strength (MEL: +8.4 +/- 1.7%) and eccentric muscle coordination (COORD: -43 +/- 4%) were significantly improved with EET but not with RET (MEL: +2.3 +/- 2.0%; COORD: -13 +/- 3%) and CT (MEL: -2.3 +/- 2.5%; COORD: -12 +/- 5%), respectively. We observed a loss of body fat (-5.0 +/- 1.1%) and thigh fat (-6.9 +/- 1.5%) in EET subjects only. Relative thigh lean mass increased with EET (+2.5 +/- 0.6%) and RET (+2.0 +/- 0.3%) and correlated negatively with type IIX/type II muscle fiber ratios. It was concluded that both RET and EET are beneficial for the elderly with regard to muscle functional and structural improvements but differ in their spectrum of effects. A training frequency of only two sessions per week seems to be the lower limit for a training stimulus to reveal measurable benefits.

Indexed as

AgedAged, 80 and overBody CompositionCognitive Behavioral TherapyExercise TestFemaleHumansLegMaleModels, BiologicalMuscle Fibers, SkeletalMuscle StrengthResistance Training

Identifiers

PMID19543908
OpenAlexW2113135336

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.