Evidence map›Paper›PMID 19543905›Full record

ArticleInternational journal of legal medicine2010

Population stratification in Argentina strongly influences likelihood ratio estimates in paternity testing as revealed by a simulation-based approach.

Ulises Toscanini, Antonio Salas, Manuel García-Magariños, Leonor Gusmão, Eduardo Raimondi

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Article in International journal of legal medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ulises ToscaniniPRICAI-FUNDACION FAVALORO, Capital Federal-Buenos Aires, Argentina.
Antonio Salas
Manuel García-Magariños
Leonor Gusmão
Eduardo Raimondi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A simulation-based analysis was carried out to investigate the potential effects of population substructure in paternity testing in Argentina. The study was performed by evaluating paternity indexes (PI) calculated from different simulated pedigree scenarios and using 15 autosomal short tandem repeats (STRs) from eight Argentinean databases. The results show important statistically significant differences between PI values depending on the dataset employed. These differences are more dramatic when considering Native American versus urban populations. This study also indicates that the use of Fst to correct for the effect of population stratification on PI might be inappropriate because it cannot account for the particularities of single paternity cases.

Indexed as

Genetics, PopulationLikelihood FunctionsPaternityAlgorithmsAnalysis of VarianceArgentinaDatabases, Nucleic AcidDNA FingerprintingGenotypeHumansMalePedigreeTandem Repeat Sequences

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.