ArticleApplied and environmental microbiology2009
Plasmid-based system for high-level gene expression and antisense gene knockdown in Bartonella henselae.
Article in Applied and environmental microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- A Stable Genetic Transformation System and Implications of the Type IV Restriction System in the Nitrogen-Fixing Plant EndosymbiontFrontiers in microbiology · 2019Article
- A family of genus-specific RNAs in tandem with DNA-binding proteins control expression of the badA major virulence factor gene in Bartonella henselae.MicrobiologyOpen · 2017Article
- Investigation of TbfA in Riemerella anatipestifer using plasmid-based methods for gene over-expression and knockdown.Scientific reports · 2016Article
- Characterization of the general stress response in Bartonella henselae.Microbial pathogenesis · 2016Article
- Zebrafish embryo model of Bartonella henselae infection.Zebrafish · 2014Article
- Article
- Heme binding proteins of Bartonella henselae are required when undergoing oxidative stress during cell and flea invasion.PloS one · 2012Article
- Heme degrading protein HemS is involved in oxidative stress response of Bartonella henselae.PloS one · 2012Article
- The BatR/BatS two-component regulatory system controls the adaptive response of Bartonella henselae during human endothelial cell infection.Journal of bacteriology · 2010Article
- The trimeric autotransporter adhesin BadA is required for in vitro biofilm formation byNPJ biofilms and microbiomesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Six broad-host-range plasmid vectors were developed to study gene expression in Bartonella henselae. The vectors were used to express a beta-galactosidase reporter gene in B. henselae and to generate antisense RNA for gene knockdown. When applied to ompR, a putative transcription response regulator of B. henselae, this antisense RNA gene knockdown strategy reduced bacterial invasion of human endothelial cells by over 60%.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.